Should imaging be a component of rheumatoid arthritis remission criteria? A comparison between traditional and modified composite remission scores and imaging …

…, AK Brown, H Keen, S Nizam, J Freeston… - Annals of the …, 2011 - ard.bmj.com
Objectives Patients can fulfil clinical criteria for remission, yet still have evidence of synovitis
detectable clinically and by ultrasound, and this is associated with structural damage. …

A diagnostic algorithm for persistence of very early inflammatory arthritis: the utility of power Doppler ultrasound when added to conventional assessment tools

JE Freeston, RJ Wakefield, PG Conaghan… - Annals of the …, 2010 - ard.bmj.com
Objectives: The aim of this study was to assess the value of power Doppler ultrasound (PDUS)
in combination with routine management in a cohort of patients with very early …

Disease remission state in patients treated with the combination of tumor necrosis factor blockade and methotrexate or with disease‐modifying antirheumatic drugs: a …

…, H Keen, S Nizam, J Freeston… - … : Official Journal of …, 2009 - Wiley Online Library
Objective For patients with rheumatoid arthritis (RA) in remission who are receiving disease‐modifying
antirheumatic drugs (DMARDs), radiographic progression correlates with imaging…

Synovitis and osteitis are very frequent in rheumatoid arthritis clinical remission: results from an MRI study of 294 patients in clinical remission or low disease activity …

…, AK Brown, UM Døhn, M Lassere, J Freeston… - The Journal of …, 2011 - jrheum.org
Objective. In rheumatoid arthritis (RA), radiographic progression may occur despite clinical
remission. This may be explained by subclinical inflammation. Magnetic resonance imaging (…

MRI and ultrasonography for diagnosis and monitoring of psoriatic arthritis

…, R Hodgson, PG Conaghan, JE Freeston - Best Practice & Research …, 2012 - Elsevier
Imaging techniques such as magnetic resonance imaging (MRI) and ultrasound (US) have
been increasingly used in psoriatic arthritis (PsA) providing additional clues to the …

[PDF][PDF] Is there subclinical synovitis in early psoriatic arthritis? A clinical comparison with gray‐scale and power Doppler ultrasound

JE Freeston, LC Coates, JL Nam… - Arthritis care & …, 2014 - Wiley Online Library
Objective Arthritis activity assessments in psoriatic arthritis (PsA) have traditionally relied on
tender and swollen joint counts, but in rheumatoid arthritis, multiple studies have …

The specificity of ultrasound-detected bone erosions for rheumatoid arthritis

…, L Terslev, EMA Hensor, JE Freeston… - Annals of the …, 2015 - ard.bmj.com
Background Bone erosion is one of the hallmarks of rheumatoid arthritis (RA), but also seen
in other rheumatic diseases. The objective of this study was to determine the specificity of …

Determining a magnetic resonance imaging inflammatory activity acceptable state without subsequent radiographic progression in rheumatoid arthritis: results from a …

…, AK Brown, UM Døhn, M Lassere, JE Freeston… - The Journal of …, 2014 - jrheum.org
Objective. To assess the predictive value of magnetic resonance imaging (MRI)-detected
subclinical inflammation for subsequent radiographic progression in a longitudinal study of …

Whole-body MRI of patients with polymyalgia rheumatica identifies a distinct subset with complete patient-reported response to glucocorticoids

…, E Harris, P Emery, R Hodgson, J Freeston… - Annals of the …, 2015 - ard.bmj.com
Objectives To determine whether whole-body MRI defines clinically relevant subgroups
within polymyalgia rheumatica (PMR) including glucocorticoid responsiveness. Methods 22 …

Regulation of entheseal IL-23 expression by IL-4 and IL-13 as an explanation for arthropathy development under dupilumab therapy

C Bridgewood, K Sharif, J Freeston, B Saleem… - …, 2021 - academic.oup.com
Objectives Dupilumab blocks the IL-4 receptor (IL-4R) and thus signalling of the ‘Th2’
cytokines IL-4 and IL-13. It has a license to treat atopic eczema and was recently linked to …