[HTML][HTML] British Lung Foundation/United Kingdom Primary Immunodeficiency Network consensus statement on the definition, diagnosis, and management of …
…, M Sheaff, PM Vaitla, GI Walters, JL Whitehouse… - The Journal of Allergy …, 2017 - Elsevier
A proportion of people living with common variable immunodeficiency disorders develop
granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a …
granulomatous-lymphocytic interstitial lung disease (GLILD). We aimed to develop a …
[HTML][HTML] The global impact of SARS-CoV-2 in 181 people with cystic fibrosis
…, M Walshaw, D Watson, JL Whitehouse - Journal of cystic …, 2020 - Elsevier
With the growing SARS-CoV-2 pandemic, we need to better understand its impact in specific
patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 …
patient groups like those with Cystic Fibrosis (CF). We report on 181 people with CF (32 …
Pseudomonas aeruginosa quorum sensing molecules correlate with clinical status in cystic fibrosis
…, D Honeybourne, JL Whitehouse… - European …, 2015 - Eur Respiratory Soc
Pseudomonas aeruginosa produces quorum sensing signal molecules that are potential
biomarkers for infection. A prospective study of 60 cystic fibrosis patients with chronic P. …
biomarkers for infection. A prospective study of 60 cystic fibrosis patients with chronic P. …
Association between Hypermutator Phenotype, Clinical Variables, Mucoid Phenotype, and Antimicrobial Resistance in Pseudomonas aeruginosa
…, EG Smith, JL Whitehouse… - Journal of clinical …, 2008 - Am Soc Microbiol
The presence of hypermutator Pseudomonas aeruginosa was associated with poorer lung
function in patients at the Adult West Midlands CF Unit. Mucoid isolates were more likely to be …
function in patients at the Adult West Midlands CF Unit. Mucoid isolates were more likely to be …
Factors associated with clinical progression to severe COVID-19 in people with cystic fibrosis: A global observational study
…, M Walshaw, D Watson, JL Whitehouse… - Journal of Cystic …, 2022 - Elsevier
Background This international study aimed to characterise the impact of acute SARS-CoV-2
infection in people with cystic fibrosis and investigate factors associated with severe …
infection in people with cystic fibrosis and investigate factors associated with severe …
[HTML][HTML] Diagnostic and prognostic significance of systemic alkyl quinolones for P. aeruginosa in cystic fibrosis: a longitudinal study
…, AR Smyth, D Honeybourne, JL Whitehouse… - Journal of Cystic …, 2017 - Elsevier
Background Pulmonary P. aeruginosa infection is associated with poor outcomes in cystic
fibrosis (CF) and early diagnosis is challenging, particularly in those who are unable to …
fibrosis (CF) and early diagnosis is challenging, particularly in those who are unable to …
A prospective randomised controlled mixed-methods pilot study of home monitoring in adults with cystic fibrosis
Background: Home monitoring (HM) is able to detect more pulmonary exacerbations (PEx)
than routine care (RC) in individuals with cystic fibrosis (CF), but there is currently no …
than routine care (RC) in individuals with cystic fibrosis (CF), but there is currently no …
[HTML][HTML] A prospective pilot study of home monitoring in adults with cystic fibrosis (HOME-CF): protocol for a randomised controlled trial
Background Home monitoring has the potential to detect early pulmonary exacerbations in
people with cystic fibrosis (CF), with consequent improvements in health outcomes and …
people with cystic fibrosis (CF), with consequent improvements in health outcomes and …
Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis
Pseudomonas aeruginosa produces specific signalling molecules, 2-alkyl-4-quinolones (AQs)
that are detectable in the sputum of adults with cystic fibrosis (CF) and who have …
that are detectable in the sputum of adults with cystic fibrosis (CF) and who have …
Who are the 10%?-Non eligibility of cystic fibrosis (CF) patients for highly effective modulator therapies
M Desai, C Hine, JL Whitehouse, K Brownlee… - Respiratory …, 2022 - Elsevier
Background The availability of mutation-specific cystic fibrosis modulator therapies has the
potential to improve the lives of children and adults with cystic fibrosis. The frequency of …
potential to improve the lives of children and adults with cystic fibrosis. The frequency of …