Pulmonary hypertension (PH) is a pathophysiological disorder that may involve multiple
clinical conditions and may be associated with a variety of cardiovascular and respiratory …

The acute effects of inhaled nitric oxide (NO) (40 ppm in air) on pulmonary (PVR) and
systemic (SVR) vascular resistance were compared with those of an intravenous infusion of …

Background— Chronic thromboembolic pulmonary hypertension (CTEPH) is often a sequel
of venous thromboembolism with fatal natural history; however, many cases can be cured by …

OBJECTIVE: Pulmonary endarterectomy is a curative surgical treatment option for the majority
of patients with chronic thromboembolic pulmonary hypertension. The current surgical …

Rationale: Pulmonary arterial hypertension in association with connective tissue disease (CTD-PAH)
has historically had a poor prognosis, with a 1-year survival rate among patients …

Background— Inflammation is a feature of pulmonary arterial hypertension (PAH), and
increased circulating levels of cytokines are reported in patients with PAH. However, to date, no …

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute
pulmonary embolism, either symptomatic or not. The occlusion of proximal pulmonary arteries …

Background. Endothelial cells release endothelium-derived relaxing factor (EDRF) in a
variety of vascular beds, including the pulmonary circulation. However, the role of EDRF-…

Objectives : Our goal was to investigate the effect of treatment with the oral dual endothelin
receptor antagonist bosentan on the hemodynamics and exercise capacity of patients with …

Background— Chronic thromboembolic pulmonary hypertension, a rare complication of acute
pulmonary embolism, is characterized by fibrothrombotic obstructions of large pulmonary …