Frailty in elderly people
Frailty is the most problematic expression of population ageing. It is a state of vulnerability to
poor resolution of homoeostasis after a stressor event and is a consequence of cumulative …
poor resolution of homoeostasis after a stressor event and is a consequence of cumulative …
[HTML][HTML] Cancer survival in five continents: a worldwide population-based study (CONCORD)
…, A Verdecchia, HH Storm, JL Young - The lancet …, 2008 - thelancet.com
Background Cancer survival varies widely between countries. The CONCORD study provides
survival estimates for 1·9 million adults (aged 15–99 years) diagnosed with a first, primary, …
survival estimates for 1·9 million adults (aged 15–99 years) diagnosed with a first, primary, …
Identification of the cellular receptor for anthrax toxin
…, J Mogridge, M Mourez, RJ Collier, JAT Young - Nature, 2001 - nature.com
The tripartite toxin secreted by Bacillus anthracis, the causative agent of anthrax, helps the
bacterium evade the immune system and can kill the host during a systemic infection. Two …
bacterium evade the immune system and can kill the host during a systemic infection. Two …
Global landscape of HIV–human protein complexes
…, T Alber, G Cagney, FD Bushman, JA Young… - Nature, 2012 - nature.com
Human immunodeficiency virus (HIV) has a small genome and therefore relies heavily on
the host cellular machinery to replicate. Identifying which host proteins and complexes come …
the host cellular machinery to replicate. Identifying which host proteins and complexes come …
[PDF][PDF] Weight, volume, and center of mass of segments of the human body
CE Clauser, JT Mc Conville, JW Young - 1969 - ntrs.nasa.gov
Knowledge of the weight, volume, and center of mass of segments of the human body is of
significance to research in such diverse fields as physical educa-tion, prosthetics, and space …
significance to research in such diverse fields as physical educa-tion, prosthetics, and space …
[PDF][PDF] A combined PET/CT scanner for clinical oncology
…, M Charron, R Roddy, J Jerin, J Young… - Journal of nuclear …, 2000 - Soc Nuclear Med
The availability of accurately aligned, whole-body anatomical (CT) and functional (PET)
images could have a significant impact on diagnosing and staging malignant disease and on …
images could have a significant impact on diagnosing and staging malignant disease and on …
HIV-1: fifteen proteins and an RNA
AD Frankel, JAT Young - Annual review of biochemistry, 1998 - annualreviews.org
Human immunodeficiency virus type 1 is a complex retrovirus encoding 15 distinct proteins.
Substantial progress has been made toward understanding the function of each protein, and …
Substantial progress has been made toward understanding the function of each protein, and …
Development and validation of an electronic frailty index using routine primary care electronic health record data
A Clegg, C Bates, J Young, R Ryan, L Nichols… - Age and …, 2016 - academic.oup.com
Background: frailty is an especially problematic expression of population ageing. International
guidelines recommend routine identification of frailty to provide evidence-based treatment…
guidelines recommend routine identification of frailty to provide evidence-based treatment…
[HTML][HTML] Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication
Human Immunodeficiency Viruses (HIV-1 and HIV-2) rely upon host-encoded proteins to
facilitate their replication. Here, we combined genome-wide siRNA analyses with interrogation …
facilitate their replication. Here, we combined genome-wide siRNA analyses with interrogation …
[HTML][HTML] Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons
There has never been a wholesale way of identifying neurons that are monosynaptically
connected either to some other cell group or, especially, to a single cell. The best available tools…
connected either to some other cell group or, especially, to a single cell. The best available tools…