Complications of intracerebral haemorrhage

JS Balami, AM Buchan - The Lancet Neurology, 2012 - thelancet.com
Intracerebral haemorrhage (ICH) is the most devastating type of stroke and is a leading
cause of disability and mortality. By contrast with advances in ischaemic stroke treatment, few …

Ischemic stroke in the elderly: an overview of evidence

RL Chen, JS Balami, MM Esiri, LK Chen… - Nature Reviews …, 2010 - nature.com
Stroke mostly occurs in elderly people and patient outcomes after stroke are highly influenced
by age. A better understanding of the causes of stroke in the elderly might have important …

Neuroprotection for ischaemic stroke: translation from the bench to the bedside

BA Sutherland, J Minnerup, JS Balami… - … Journal of Stroke, 2012 - journals.sagepub.com
Neuroprotection seeks to restrict injury to the brain parenchyma following an ischaemic insult
by preventing salvageable neurons from dying. The concept of neuroprotection has shown …

Neurological complications of acute ischaemic stroke

JS Balami, RL Chen, IQ Grunwald… - The Lancet …, 2011 - thelancet.com
Complications after ischaemic stroke, including both neurological and medical complications,
are a major cause of morbidity and mortality. Neurological complications, such as brain …

Complications of endovascular treatment for acute ischemic stroke: prevention and management

JS Balami, PM White, PJ McMeekin… - … Journal of Stroke, 2018 - journals.sagepub.com
Endovascular mechanical thrombectomy (MT) for the treatment of acute stroke due to large
vessel occlusion has evolved significantly with the publication of multiple positive …

A systematic review and meta-analysis of randomized controlled trials of endovascular thrombectomy compared with best medical treatment for acute ischemic stroke

JS Balami, BA Sutherland… - … Journal of Stroke, 2015 - journals.sagepub.com
Background Acute ischemic strokes involving occlusion of large vessels usually recanalize
poorly following treatment with intravenous thrombolysis. Recent studies have shown higher …

The exact science of stroke thrombolysis and the quiet art of patient selection

JS Balami, G Hadley, BA Sutherland, H Karbalai… - Brain, 2013 - academic.oup.com
The science of metric-based patient stratification for intravenous thrombolysis, revolutionized
by the landmark National Institute of Neurological Disorders and Stroke trial, has …

The transient intraluminal filament middle cerebral artery occlusion model as a model of endovascular thrombectomy in stroke

…, AA Neuhaus, Y Couch, JS Balami… - Journal of Cerebral …, 2016 - journals.sagepub.com
The clinical relevance of the transient intraluminal filament model of middle cerebral artery
occlusion (tMCAO) has been questioned due to distinct cerebral blood flow profiles upon …

Complications associated with recombinant tissue plasminogen activator therapy for acute ischaemic stroke

JS Balami, BA Sutherland… - CNS & Neurological …, 2013 - ingentaconnect.com
Intravenous recombinant human tissue plasminogen activator (rtPA, formulated as alteplase)
is the primary therapy for acute ischaemic stroke by breaking down a clot of an occluded …

[HTML][HTML] Stroke in the time of circadian medicine

P Mergenthaler, JS Balami, AA Neuhaus… - Circulation …, 2024 - Am Heart Assoc
Time-of-day significantly influences the severity and incidence of stroke. Evidence has
emerged not only for circadian governance over stroke risk factors, but also for important …