User profiles for Karim Sacre

Karim Sacre

Professeur de Médecine, Université Paris Cité
Verified email at aphp.fr
Cited by 4365

[HTML][HTML] Hydroxychloroquine is associated with impaired interferon-alpha and tumor necrosis factor-alpha production by plasmacytoid dendritic cells in systemic lupus …

K Sacre, LA Criswell, JM McCune - Arthritis research & therapy, 2012 - Springer
Introduction Plasmacytoid dendritic cells (pDCs) constitutively express two members of the
Toll-like receptor (TLR) family, TLR-9 and TLR-7, through which they can be stimulated to …

Epidemiology of primary Sjögren's syndrome in a French multiracial/multiethnic area

…, O Meyer, J Ramanoelina, K Sacré… - Arthritis care & …, 2014 - Wiley Online Library
Objective To describe the epidemiology of primary Sjögren's syndrome (SS) in a multiracial/multiethnic
population. Methods A cross‐sectional study with 5 case‐retrieval sources …

Determinants of hydroxychloroquine blood concentration variations in systemic lupus erythematosus

…, L Sailler, F Ackermann, T Papo, K Sacre… - Arthritis & …, 2015 - Wiley Online Library
Objective Blood concentrations of hydroxychloroquine (HCQ) vary widely among patients
with systemic lupus erythematosus (SLE). A pharmacokinetic/pharmacodynamic relationship …

[HTML][HTML] Positron emission tomography and computed tomography angiography for the diagnosis of giant cell arteritis: a real-life prospective study

…, T Goulenok, A Dossier, P Dieude, T Papo, K Sacre - Medicine, 2016 - journals.lww.com
The use of 18F-fluoro-deoxyglucose positron emission tomography scan (FDG-PET) and
computed tomography angiography (CTA) to improve accuracy of diagnosis of giant cell …

[HTML][HTML] Autoreactive IgE is prevalent in systemic lupus erythematosus and is associated with increased disease activity and nephritis

…, C Jiang, TK Ricks, MM Bonelli, J Scheffel, K Sacre… - PloS one, 2014 - journals.plos.org
The presence of autoantibodies in systemic lupus erythematosus, particularly those of the
IgG subclass, have long been associated with disease onset and activity. Here we explored …

Arterial thrombotic events in adult inpatients with COVID-19

…, JF Timsit, Y Yazdanpanah, T Papo, K Sacre - Mayo Clinic …, 2021 - Elsevier
Objective To evaluate the clinical course of and risk factors for arterial thrombotic events in
adult inpatients with coronavirus disease 2019 (COVID-19). Methods All consecutive adult …

Giant cell arteritis–related stroke: a retrospective multicenter case-control study

…, K Ly, E Touzé, B Bonnotte, A Aouba, K Sacré… - The Journal of …, 2017 - jrheum.org
Objective. Our aim was to describe patients with giant cell arteritis (GCA)–related stroke and
to compare them with a control group of GCA patients without stroke. Methods. We created a …

Central nervous system involvement in Whipple disease: clinical study of 18 patients and long-term follow-up

C Compain, K Sacre, X Puéchal, I Klein… - Medicine, 2013 - journals.lww.com
Whipple disease (WD) is a rare multisystemic infection with a protean clinical presentation.
The central nervous system (CNS) is involved in 3 situations: CNS involvement in classic WD, …

Treatment of neurosarcoidosis: a comparative study of methotrexate and mycophenolate mofetil

S Bitoun, D Bouvry, R Borie, M Mahevas, K Sacre… - Neurology, 2016 - AAN Enterprises
Objective: To compare the efficacy of methotrexate (MTX) and mycophenolate mofetil (MMF)
in the prevention of relapses in neurosarcoidosis. Methods: We conducted a retrospective …

[HTML][HTML] Risk of autoimmune diseases and human papilloma virus (HPV) vaccines: Six years of case-referent surveillance

…, G Hayem, O Meyer, E Pasqualoni, K Sacre… - Journal of …, 2017 - Elsevier
Background Safety of HPV vaccines is still in question due to reports of autoimmune diseases
(ADs) following HPV immunization. Objectives To assess the risk of ADs associated with …