[HTML][HTML] Urine steroid metabolomics for the differential diagnosis of adrenal incidentalomas in the EURINE-ACT study: a prospective test validation study

…, AE Taylor, RP Sutcliffe, P Guest, K Skordilis… - The lancet Diabetes & …, 2020 - thelancet.com
Background Cross-sectional imaging regularly results in incidental discovery of adrenal
tumours, requiring exclusion of adrenocortical carcinoma (ACC). However, differentiation is …

Heterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: results from a large patient cohort

…, B O'Sullivan, P Taniere, K Skordilis… - The Journal of …, 2015 - academic.oup.com
Context: Pituitary adenomas and pheochromocytomas/paragangliomas (pheo/PGL) can occur
in the same patient or in the same family. Coexistence of the two diseases could be due to …

[HTML][HTML] The podoplanin-CLEC-2 axis inhibits inflammation in sepsis

…, B Grygielska, SW Smith, K Skordilis… - Nature …, 2017 - nature.com
Platelets play a critical role in vascular inflammation through the podoplanin and collagen/fibrin
receptors, C-type-lectin-like-2 (CLEC-2) and glycoprotein VI (GPVI), respectively. Both …

An international Ki67 reproducibility study in adrenal cortical carcinoma

…, AJ Gill, X Matias-Guiu, K Skordilis… - The American Journal …, 2016 - journals.lww.com
Despite the established role of Ki67 labeling index in prognostic stratification of adrenocortical
carcinomas and its recent integration into treatment flow charts, the reproducibility of the …

[HTML][HTML] The spectrum of renal allograft failure

…, C Collins, D Briggs, S Ball, A Sharif, K Skordilis… - PLoS …, 2016 - journals.plos.org
Background Causes of “true” late kidney allograft failure remain unclear as study selection
bias and limited follow-up risk incomplete representation of the spectrum. Methods We …

Performance of DNA-based biomarkers for classification of adrenocortical carcinoma: A prognostic study

…, A Prete, S Kircher, K Skordilis… - European Journal of …, 2023 - academic.oup.com
Objective Adrenocortical carcinoma (ACC) is a rare aggressive malignancy with
heterogeneous clinical outcomes. Recent studies proposed a combination of clinical/histopathological …

Defining renal phenotype in Alström syndrome

…, RP Marshall, M Belal, K Skordilis… - Nephrology Dialysis …, 2020 - academic.oup.com
Background Alström syndrome (AS) is a rare autosomal recessive ciliopathy with a wide
spectrum of clinical features, including cone–rod retinal dystrophy, neuronal deafness, severe …

[HTML][HTML] SDHA mutated paragangliomas may be at high risk of metastasis

…, WM Drake, D Iacovazzo, K Skordilis… - Endocrine-related …, 2017 - erc.bioscientifica.com
We report the clinical outcomes of eleven patients with succinate dehydrogenase subunit A (SDHA)
germline mutations from three UK tertiary referral centres to highlight a more diverse …

[HTML][HTML] A patient with a germline SDHB mutation presenting with an isolated pituitary macroprolactinoma

…, D Collier, J Drummond, K Skordilis… - … & metabolism case …, 2018 - edm.bioscientifica.com
Symptomatic pituitary adenomas occur with a prevalence of approximately 0.1% in the general
population. It is estimated that 5% of pituitary adenomas occur in a familial setting, either …

Chronic inflammation and other changes are significant components of clinically fibrotic strictures in Crohn's disease: a histological study of resected strictures …

…, R Cooney, S Ghosh, K Skordilis - European journal of …, 2020 - journals.lww.com
… g ; Iacucci, Marietta a,,b,,c ; Cooney, Rachel d ; Ghosh, Subrata a,,b,,c,,* ; Skordilis, Kassiani
e,,* … * Kassiani Skordilis and Subrata Ghosh contributed equally to the writing of this article. …