Our understanding of the physiological systems that regulate food intake and body weight
has increased immensely over the past decade. Brain centres, including the hypothalamus, …

Our knowledge of the physiological systems controlling energy homeostasis has increased
dramatically over the last decade. The roles of peripheral signals from adipose tissue, …

This study investigated the effect of subcutaneously administered oxyntomodulin on body
weight in healthy overweight and obese volunteers. Participants self-administered saline or …

Anorexia and malnutrition confer significant morbidity and mortality to patients with end-stage
kidney disease but are resistant to therapy. The aim of this study was to determine whether …

Many peptides are synthesized and released from the gastrointestinal tract and pancreas,
including pancreatic polypeptide (PP) and the products of the gastrointestinal L cells, glucagon…

Malnutrition is a common complication in patients on dialysis and is strongly associated with
poor prognosis. Effective therapy could substantially improve morbidity and mortality, but …

Signals generated by the gastrointestinal tract are able to regulate appetite and influence
body weight. Ghrelin is an orexigenic peptide produced by the stomach. Satiety signals …

This review examined the risk of cardiovascular disease in adults with metabolically healthy
overweight/obesity. A systematic review and meta‐analysis using data from Medline, …

OBJECTIVE Peptide YY 3–36 (PYY 3–36 ), a Y2 receptor agonist, and oxyntomodulin, a
glucagon-like peptide 1 (GLP-1) receptor agonist, are cosecreted by intestinal L-cells after each …

Diabetes is a chronic, complex condition requiring sound knowledge and self-management
skills to optimize glycemic control and health outcomes. Dietary intake and physical activity …