The cardiovascular actions of the magnesium ion at pharmacological concentrations
include coronary and systemic vasodilatation, platelet inhibition, and antiarrhythmic effects. …

Background The ACE gene is characterized by a polymorphism based on the presence (insertion
[I]) or absence (deletion [D]) within intron 16 of a 287-basepair alu repeat sequence, …

The second Leicester Intravenous Magnesium Intervention Trial (LIMIT-2) examined the effect
of an intravenous regimen of magnesium sulphate in 2316 patients with suspected acute …

Methods and results We recruited 55 patients requiring measurement of blood gas pressures
from patients admitted urgently to Kettering General Hospital. The study's protocol was …

Seven randomised clinical trials in a total of over 1,300 patients have examined the effects
of intravenous magnesium salts (chloride or sulphate) given early after acute myocardial …

In recent times, there has been an unprecedented level of public interest and active debate
regarding the regulation of medical devices. This is in light of the topical, rather dissimilar, …

Background There is conclusive evidence from clinical trials that thrombolytic therapy reduces
mortality in acute myocardial infarction (AMI). But still only a minority of patients admitted …

Aims Long-term beta-blockade reduced mortality after acute myocardial infarction by about
a quarter in a series of published trials. Representative data on beta-blocker use for …

32 P-Postlabelling of DNA extracted from the livers obtained from seven women receiving
tamoxifen (20 mg either once or twice daily) was compared with liver DNA from seven …

QTc Dispersion. Introduction: QTc dispersion has traditionally been calculated from all 12
leads of a standard electrocardiogram (ECG). It is possible that alternative, quicker methods …