for digital applications (smartphones, etc.). These versions are abridged and thus, for more
detailed information, the user should always access to the full text version of the guidelines, …

Aims To assess tolerability and optimal time point for initiation of sacubitril/valsartan in
patients stabilised after acute heart failure (AHF). Methods and results TRANSITION was a …

Background Vagus nerve stimulation (VNS) is currently used to treat refractory epilepsy and
is being investigated as a potential therapy for a range of conditions, including heart failure, …

Aims The 6 min walk test (6MWT) is commonly used in clinical trials to assess treatments for
heart failure, but its ability to distinguish between effective and ineffective treatments is …

Background : Patients with chronic heart failure (HF) secondary to left ventricular systolic
dysfunction (LVSD) are frequently deficient in vitamin D. Low vitamin D levels are associated …

Aims Remote management of heart failure using implantable electronic devices (REM-HF)
aimed to assess the clinical and cost-effectiveness of remote monitoring (RM) of heart failure …

Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues
are functionally associated with skeletal muscle, adipose tissue metabolism and systemic …

Background: It is unclear whether diabetes mellitus (DM) is an adverse prognostic factor in
chronic heart failure (CHF) of ischaemic and non-ischaemic aetiology managed with …

Traditional explanations for the symptoms of fatigue and breathlessness experienced by
patients with chronic heart failure (CHF) focus on how reduced cardiac output on exercise leads …

Background— Therapies for patients with chronic heart failure caused by left ventricular
systolic dysfunction have advanced substantially over recent decades. The cumulative effect of …