Drug resistance and the solid tumor microenvironment
O Trédan, CM Galmarini, K Patel… - Journal of the National …, 2007 - academic.oup.com
Resistance of human tumors to anticancer drugs is most often ascribed to gene mutations,
gene amplification, or epigenetic changes that influence the uptake, metabolism, or export of …
gene amplification, or epigenetic changes that influence the uptake, metabolism, or export of …
Estimated indirect cost savings of using telehealth among nonelderly patients with cancer
Importance Patients with cancer typically have greater financial hardships and time costs
than individuals without cancer. The COVID-19 pandemic has exacerbated this, while posing …
than individuals without cancer. The COVID-19 pandemic has exacerbated this, while posing …
Quantitative assessment of microplastic in sandy beaches of Gujarat state, India
The present study was carried out to quantify microplastic prevalence among 20 sandy
beaches on the Gujarat coast. Beaches were categorised into three different classes, viz. low-…
beaches on the Gujarat coast. Beaches were categorised into three different classes, viz. low-…
Estimated carbon emissions savings with shifts from in-person visits to telemedicine for patients with cancer
Importance While the health care community advocates broadly for climate change policy,
medical professionals can look within care practices to assess their contribution to carbon …
medical professionals can look within care practices to assess their contribution to carbon …
Quantitative assessment of microplastic contamination in muddy shores of Gulf of Khambhat, India
Microplastics (MPs) have become a global concern due to their widespread distribution in
marine ecosystems. The present study was aimed to assess MPs contamination in 21 muddy …
marine ecosystems. The present study was aimed to assess MPs contamination in 21 muddy …
Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes
A strategy is proposed to profile compounds for mechanism-based inactivation of CYP3A4,
CYP2C19, CYP2C9, CYP2D6, and CYP1A2 based on an apparent partition ratio screen. …
CYP2C19, CYP2C9, CYP2D6, and CYP1A2 based on an apparent partition ratio screen. …
Epigenetic dysregulation of hairy and enhancer of split 4 (HES4) is associated with striatal degeneration in postmortem Huntington brains
To investigate epigenetic contributions to Huntington's disease (HD) pathogenesis, we
carried out genome-wide mapping of the transcriptional mark, trimethyl-histone H3-lysine 4 (…
carried out genome-wide mapping of the transcriptional mark, trimethyl-histone H3-lysine 4 (…
SARS-CoV-2 vaccine-induced subacute thyroiditis
KR Patel, ME Cunnane, DG Deschler - American Journal of Otolaryngology, 2022 - Elsevier
3. Discussion Subacute thyroiditis is an inflammatory condition of the thyroid gland often
precipitated by a viral illness with diagnosis based upon characteristic symptomatology (fevers, …
precipitated by a viral illness with diagnosis based upon characteristic symptomatology (fevers, …
[HTML][HTML] Concurrent cetuximab and nivolumab as a second-line or beyond treatment of patients with recurrent and/or metastatic head and neck squamous cell …
Simple Summary To improve overall survival (OS), we evaluated a combination of cetuximab
and nivolumab for toxicity and efficacy in patients with incurable recurrent and/or metastatic …
and nivolumab for toxicity and efficacy in patients with incurable recurrent and/or metastatic …
Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo
…, N Vitali, S Bhattacharya, C Blackwell, K Patel… - Molecular cancer …, 2021 - AACR
B-cell maturation antigen (BCMA) is an attractive therapeutic target highly expressed on
differentiated plasma cells in multiple myeloma and other B-cell malignancies. GSK2857916 (…
differentiated plasma cells in multiple myeloma and other B-cell malignancies. GSK2857916 (…