User profiles for Laura Matthews
Laura C MatthewsUniversity Academic Fellow, University of Leeds Verified email at leeds.ac.uk Cited by 2241 |
The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines
Diurnal variation in inflammatory and immune function is evident in the physiology and
pathology of humans and animals, but molecular mechanisms and mediating cell types that …
pathology of humans and animals, but molecular mechanisms and mediating cell types that …
An epithelial circadian clock controls pulmonary inflammation and glucocorticoid action
The circadian system is an important regulator of immune function. Human inflammatory lung
diseases frequently show time-of-day variation in symptom severity and lung function, but …
diseases frequently show time-of-day variation in symptom severity and lung function, but …
Current concepts in glucocorticoid resistance
Glucocorticoids (GCs) are the most potent anti-inflammatory agents known. A major factor
limiting their clinical use is the wide variation in responsiveness to therapy. The high doses of …
limiting their clinical use is the wide variation in responsiveness to therapy. The high doses of …
[PDF][PDF] Social media and the evolution of corporate communications
L Matthews - The Elon Journal of Undergraduate Research in …, 2010 - Citeseer
Social media has revolutionized corporate communications, rapidly changing the way that
public relations campaigns or programs are distributed and measured. Rather than the …
public relations campaigns or programs are distributed and measured. Rather than the …
The clock gene Bmal1 inhibits macrophage motility, phagocytosis, and impairs defense against pneumonia
…, B Saer, T Hussell, LC Matthews… - Proceedings of the …, 2020 - National Acad Sciences
The circadian clock regulates many aspects of immunity. Bacterial infections are affected by
time of day, but the mechanisms involved remain undefined. Here we show that loss of the …
time of day, but the mechanisms involved remain undefined. Here we show that loss of the …
Examining the assumptive world views of parents bereaved by accident, murder, and illness
LT Matthews, SJ Marwit - OMEGA-Journal of Death and …, 2004 - journals.sagepub.com
The present study examines the impact of various types of loss on the assumptive world
views of bereaved parents. The World Assumptions Scale (WAS) and the Revised Grief …
views of bereaved parents. The World Assumptions Scale (WAS) and the Revised Grief …
miR-145 suppresses embryo–epithelial juxtacrine communication at implantation by modulating maternal IGF1R
YJ Kang, M Lees, LC Matthews… - Journal of cell …, 2015 - journals.biologists.com
Successful implantation requires the synchronization of viable embryonic development with
endometrial receptivity. The mechanisms allowing for the initiation of crosstalk between the …
endometrial receptivity. The mechanisms allowing for the initiation of crosstalk between the …
[HTML][HTML] REVERBa couples the circadian clock to hepatic glucocorticoid action
The glucocorticoid receptor (GR) is a major drug target in inflammatory disease. However,
chronic glucocorticoid (GC) treatment leads to disordered energy metabolism, including …
chronic glucocorticoid (GC) treatment leads to disordered energy metabolism, including …
Caveolin mediates rapid glucocorticoid effects and couples glucocorticoid action to the antiproliferative program
L Matthews, A Berry, V Ohanian… - Molecular …, 2008 - academic.oup.com
Many glucocorticoid (Gc) actions are of rapid onset and therefore require acute regulation of
intracellular signaling cascades. Integration of diverse extracellular signals requires cross-…
intracellular signaling cascades. Integration of diverse extracellular signals requires cross-…
Meaning reconstruction in the context of religious coping: Rebuilding the shattered assumptive world
LT Matthews, SJ Marwit - OMEGA-Journal of Death and …, 2006 - journals.sagepub.com
Recently research studies have begun to examine the theory that religion may help bereaved
individuals to provide meaning (or an explanation) to an otherwise inconceivable event. In …
individuals to provide meaning (or an explanation) to an otherwise inconceivable event. In …