Although immunosuppression has long been recognized in Hodgkin lymphoma (HL), the
underlying basis for the lack of an effective immune response against the tumor remains …

Importance In patients who require mechanical ventilation for acute hypoxemic respiratory
failure, further reduction in tidal volumes, compared with conventional low tidal volume …

Well-placed local anaesthetics (LAs) can yield great clinical benefits. But systemic toxicity
related to their use can be devastating. The highly publicized case in 2004 of Mayra Cabrera, …

Pain is a common and distressing symptom experienced by intensive care patients.
Assessing pain in this environment is challenging, and published guidelines have been …

Common causes of death in COVID-19 due to SARS-CoV-2 include thromboembolic disease,
cytokine storm and adult respiratory distress syndrome (ARDS). Our aim was to develop a …

Background and Objectives: The bronchoscopic microsample (BMS) probe allows direct
epithelial lining fluid (ELF) level measurement without saline lavage. We investigated whether …

Background COVID-19 is a global health emergency. Recent data indicate a 50% mortality
rate across UK intensive care units. Methods A single institution, two-centre retrospective …

Background UK data suggest 6% of COVID-19 hospital admissions are either currently
pregnant or immediately post-partum. However, the current literature suggests that if COVID-19 …

This section asks for information about the work that you have submitted for publication. The
time frame for this reporting is that of the work itself, from the initial conception and planning …

Objectives This study examines the histological findings of tracheal tissue samples obtained
from COVID‐19 positive mechanically ventilated patients, to assess the degree of tracheal …