Repression of osteocyte Wnt/β‐catenin signaling is an early event in the progression of renal osteodystrophy
…, W Tang, LM dos Reis, S Ryan, L Phillips… - Journal of Bone and …, 2012 - academic.oup.com
Chronic kidney disease–mineral bone disorder (CKD‐MBD) is defined by abnormalities in
mineral and hormone metabolism, bone histomorphometric changes, and/or the presence of …
mineral and hormone metabolism, bone histomorphometric changes, and/or the presence of …
Cochlear implantation in children under the age of two—what do the outcomes show us?
…, MS Quevedo, J Martin, WS Dieler, L Phillips - International journal of …, 2004 - Elsevier
Objective: Literature that discusses the benefits of cochlear implantation (CI) in children
under the age of two is limited. Previous concerns about surgical risk have been raised and …
under the age of two is limited. Previous concerns about surgical risk have been raised and …
[HTML][HTML] A systematic review and meta-analysis of suicidality in autistic and possibly autistic people without co-occurring intellectual disability
V Newell, L Phillips, C Jones, E Townsend, C Richards… - Molecular autism, 2023 - Springer
Background Suicidality is highly prevalent in autistic people without co-occurring intellectual
disabilities, and high autistic traits are found in adults who have attempted suicide. However…
disabilities, and high autistic traits are found in adults who have attempted suicide. However…
Npt2b deletion attenuates hyperphosphatemia associated with CKD
…, W Song, J Boulanger, S Ryan, L Phillips… - Journal of the …, 2012 - journals.lww.com
The incidence of cardiovascular events and mortality strongly correlates with serum phosphate
in individuals with CKD. The Npt2b transporter contributes to maintaining phosphate …
in individuals with CKD. The Npt2b transporter contributes to maintaining phosphate …
[HTML][HTML] Mechanisms and regulation of IL-22-mediated intestinal epithelial homeostasis and repair
…, S Wilson, V Pivorunas, J Karman, L Phillips… - Life Sciences, 2021 - Elsevier
Aims Ulcerative colitis and Crohn's disease, collectively known as inflammatory bowel
disease (IBD), are chronic inflammatory disorders of the intestine for which key elements in …
disease (IBD), are chronic inflammatory disorders of the intestine for which key elements in …
Epiregulin is a dendritic cell–derived EGFR ligand that maintains skin and lung fibrosis
…, J Karman, TL Carr, JB Wetter, L Phillips… - Science …, 2022 - science.org
Immune cells are fundamental regulators of extracellular matrix (ECM) production by fibroblasts
and have important roles in determining extent of fibrosis in response to inflammation. …
and have important roles in determining extent of fibrosis in response to inflammation. …
[HTML][HTML] Anti-microRNA-21 therapy on top of ACE inhibition delays renal failure in Alport syndrome mouse models
…, J Boulanger, F Craciun, EY Xu, Y Zhang, L Phillips… - Cells, 2022 - mdpi.com
Col4a3 −/− Alport mice serve as an animal model for renal fibrosis. MicroRNA-21 (miR-21)
expression has been shown to be increased in the kidneys of Alport syndrome patients. Here, …
expression has been shown to be increased in the kidneys of Alport syndrome patients. Here, …
[HTML][HTML] Antisense oligonucleotide-mediated suppression of muscle glycogen synthase 1 synthesis as an approach for substrate reduction therapy of Pompe disease
…, KM Taylor, RJ Moreland, RK Scheule, L Phillips… - … therapy-Nucleic acids, 2014 - cell.com
Pompe disease is an autosomal recessive disorder caused by a deficiency of acid α-glucosidase
(GAA; EC 3.2.1.20) and the resultant progressive lysosomal accumulation of glycogen …
(GAA; EC 3.2.1.20) and the resultant progressive lysosomal accumulation of glycogen …
Systemic delivery of a Peptide-linked morpholino oligonucleotide neutralizes mutant RNA toxicity in a mouse model of myotonic dystrophy
…, IH Wu, T Weeden, CA Nelson, L Phillips… - nucleic acid …, 2013 - liebertpub.com
Expansions of CUG trinucleotide sequences in RNA transcripts provide the basis for toxic
RNA gain-of-function that leads to detrimental changes in RNA metabolism. A CTG repeat …
RNA gain-of-function that leads to detrimental changes in RNA metabolism. A CTG repeat …
[HTML][HTML] Optimized culture conditions for improved growth and functional differentiation of mouse and human colon organoids
…, H Knight, L Patnaude, X Wu, L Phillips… - Frontiers in …, 2021 - frontiersin.org
Background & Aims Diligent side-by-side comparisons of how different methodologies affect
growth efficiency and quality of intestinal colonoids have not been performed leaving a gap …
growth efficiency and quality of intestinal colonoids have not been performed leaving a gap …