Purpose: Tumor hypoxia fuels an aggressive tumor phenotype and confers resistance to
anticancer treatments. We conducted a clinical trial to determine whether the antimalarial drug …

Background Pre-clinically, phosphoinositide 3-kinase (PI3K) inhibition radiosensitises
tumours by increasing intrinsic radiosensitivity and by reducing tumour hypoxia. We assessed …

Malignant pleural mesothelioma (MPM) is an aggressive cancer, associated with poor prognosis.
We assessed the feasibility of patient-derived cell cultures to serve as an ex vivo model …

Uterine Leiomyoma is a common gynaecological pathology and one of the common indications
for myomectomy and hysterectomy. Intravascular Leiomyomatosis (IVL), however, is an …

… Ashraghi 1 , Mary Quirke 2 , Radu Mihai 3 , Daniel Ajzensztejn 4 , Robert Stuart 4 , Mark
McCole 5 , Louise Fryearson 6 , Camilla Buckley 1 , Maria I. Leite 1 … Cite this abstract as …

We describe a rare case of a 69-year-old woman presenting with sudden onset right-sided
weakness, sensory disturbance and dysarthria due to a left-middle cerebral artery territory …

Our work aims to link pathology with radiology with the goal to improve the early detection of
lung cancer. Rather than utilising a set of predefined radiomics features, we propose to …

Identifying subtypes and histological patterns is crucial for lung cancer diagnosis and
treatment. Nevertheless, datasets with complete subtyping annotations are scarce, and most …

Background The thymus plays a key role in development T lymphocytes and immune self-tolerance.
This process is disrupted in thymic malignancy, resulting in patients developing an …

A 45-year-old Caucasian woman was referred for investigation of recurrent chest infections.
She had been treated over the previous 9 months for recurrent symptoms characterised by …