The pathogenesis of coma in severe Plasmodium falciparum malaria remains poorly understood.
Obstruction of the brain microvasculature because of sequestration of parasitized red …

Background The genetic cause of primary immunodeficiency disease (PID) carries prognostic
information. Objective We conducted a whole-genome sequencing study assessing a …

Background Little is known about the mortality of hospital-acquired (nosocomial) COVID-19
infection globally. We investigated the risk of mortality and critical care admission in …

CORRESPONDENCE lifetime smoking score were also associated with increased risk of
severe COVID-19 with respiratory failure and hospitalization with COVID-19 (Figure). Similar …

BackgroundSchizophrenia affects 1% of the population. Clozapine is the only medication
licensed for treatment-resistant schizophrenia and is intensively monitored to prevent harm …

Testing for severe acute respiratory coronavirus 2 (SARS-CoV-2), which causes covid-19, is
complex and politically sensitive. Seroprevalence studies use antibodies as markers of …

Background: Detecting antibody responses during and after SARS-CoV-2 infection is
essential in determining the seroepidemiology of the virus and the potential role of antibody in …

Conclusions The main features of respiratory mechanics, the response to treatment (such as
the oxygenation response to LRMs or prone position), and prognosis are similar in COVID-…

Detecting antibody responses during and after SARS‐CoV‐2 infection is essential in
determining the seroepidemiology of the virus and the potential role of antibody in disease. …

In contrast to reports made early in the pandemic, we show XLA patients remain susceptible
to severe disease. Persistent infection was common and is likely to carry a significant …