BACKGROUND: Common autoimmune disorders tend to coexist in the same subjects and
to cluster in families. METHODS: We performed a cross-sectional multicenter study of 3286 …

Early case control studies found association of the DRB1 allele, DR3, with Graves’ disease (GD).
Recent reports, claim the DQA1 allele, DQA1*0501, to be the primary susceptibility …

Case-control studies suggest that the CTLA-4 gene may be a susceptibility locus for Graves’
disease. The previously reported A/G polymorphism at position 49 in exon 1 of the CTLA-4 …

Background This short clinical guideline aims to improve the care of acutely ill patients in
hospital by giving evidence based recommendations on the best way to identify and manage …

Insulin autoantibodies (IAA) were studied in newly diagnosed insulin-dependent diabetics
before the start of insulin treatment and in unaffected identical twins of insulin-dependent …

BACKGROUND None of the existing options for long‐term testosterone replacement therapy
(TRT) for hypogonadal men are ideal. Depot replacement at frequent intervals and implants …

Millions of women are treated with hormone replacement therapy (HRT) for relief of menopausal
symptoms, including vasomotor flushes and sweats for which oestrogen is uniquely and …

Consultant-led medical admission units have been developed as one method of managing
the increasing number of acute medical emergencies. The need to document such …

Background: The UK Department of Health is considering a single, generic multi-source
feedback (MSF) questionnaire to inform revalidation. Method: Evaluation of an implementation …

The OHE Compendium of Health Statistics is the one-stop statistical source specially designed
for easy use by anyone interested in the UK health care sector and the NHS. It contains …