User profiles for Massimo Federici
Massimo FedericiDept. of Systems Medicine - University of Rome Tor Vergata Verified email at uniroma2.it Cited by 39317 |
2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: The Task Force for diabetes, pre-diabetes …
Health professionals are encouraged to take the Guidelines fully into account when
exercising their clinical judgment, as well as in the determination and the implementation of …
exercising their clinical judgment, as well as in the determination and the implementation of …
[PDF][PDF] Mandibuloacral dysplasia is caused by a mutation in LMNA-encoding lamin A/C
…, C Massart, F Capon, P Sbraccia, M Federici… - The American Journal of …, 2002 - cell.com
Mandibuloacral dysplasia (MAD) is a rare autosomal recessive disorder, characterized by
postnatal growth retardation, craniofacial anomalies, skeletal malformations, and mottled …
postnatal growth retardation, craniofacial anomalies, skeletal malformations, and mottled …
MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1
Background— Aging is a major risk factor for the development of atherosclerosis and
coronary artery disease. Through a microarray approach, we have identified a microRNA (miR-217…
coronary artery disease. Through a microarray approach, we have identified a microRNA (miR-217…
Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women
Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …
Defects of the insulin receptor substrate (IRS) system in human metabolic disorders
Insulin receptor substrate (IRS) molecules are key mediators in insulin signaling and play a
central role in maintaining basic cellular functions such as growth, survival, and metabolism. …
central role in maintaining basic cellular functions such as growth, survival, and metabolism. …
2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes: Developed by the task force on the management of cardiovascular …
N Marx, M Federici, K Schütt… - European heart …, 2023 - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient’s interest …
off-label use of medication should be limited to situations where it is in the patient’s interest …
High glucose causes apoptosis in cultured human pancreatic islets of Langerhans: a potential role for regulation of specific Bcl family genes toward an apoptotic cell …
M Federici, M Hribal, L Perego, M Ranalli… - Diabetes, 2001 - Am Diabetes Assoc
Type 2 diabetes is characterized by insulin resistance and inadequate insulin secretion. In
the advanced stages of the disease, β-cell dysfunction worsens and insulin therapy may be …
the advanced stages of the disease, β-cell dysfunction worsens and insulin therapy may be …
Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial …
M Federici, R Menghini, A Mauriello, ML Hribal… - Circulation, 2002 - Am Heart Assoc
Background— Hyperglycemia impairs functional properties of cytosolic and nuclear proteins
via O-linked glycosylation modification (O-GlcNAcylation). We studied the effects of O-…
via O-linked glycosylation modification (O-GlcNAcylation). We studied the effects of O-…
Metabolically healthy versus metabolically unhealthy obesity
C Iacobini, G Pugliese, CB Fantauzzi, M Federici… - Metabolism, 2019 - Elsevier
Obesity-related disease complications reduce life quality and expectancy and increase
health-care costs. Some studies have suggested that obesity not always entails metabolic …
health-care costs. Some studies have suggested that obesity not always entails metabolic …
A novel pharmacologic inhibitor of the NLRP3 inflammasome limits myocardial injury after ischemia–reperfusion in the mouse
…, N Tranchida, SW Rose, M Federici… - Journal of …, 2014 - journals.lww.com
Background: The formation of the NLRP3 inflammasome in the heart during acute myocardial
infarction amplifies the inflammatory response and mediates further damage. Glyburide …
infarction amplifies the inflammatory response and mediates further damage. Glyburide …