Iron deficiency anaemia in pregnancy: a contemporary review

CS Benson, A Shah, MC Frise, CJ Frise - Obstetric medicine, 2021 - journals.sagepub.com
Iron deficiency anaemia is a global health problem, which particularly affects pregnant
women. Iron deficiency anaemia during pregnancy is associated with increased maternal and …

Non-contact measurement of oxygen saturation with an RGB camera

…, M Villarroel, J Jorge, J Daly, MC Frise… - Biomedical optics …, 2015 - opg.optica.org
A novel method (Sophia) is presented to track oxygen saturation changes in a controlled
environment using an RGB camera placed approximately 1.5 m away from the subject. The …

Iron, oxygen, and the pulmonary circulation

MC Frise, PA Robbins - Journal of Applied Physiology, 2015 - journals.physiology.org
The human pulmonary vasculature vasoconstricts in response to a reduction in alveolar
oxygen tension, a phenomenon termed hypoxic pulmonary vasoconstriction (HPV). This review …

[HTML][HTML] Clinical iron deficiency disturbs normal human responses to hypoxia

MC Frise, HY Cheng, AH Nickol… - The Journal of …, 2016 - Am Soc Clin Investig
BACKGROUND. Iron bioavailability has been identified as a factor that influences cellular
hypoxia sensing, putatively via an action on the hypoxia-inducible factor (HIF) pathway. We …

Intracellular iron deficiency in pulmonary arterial smooth muscle cells induces pulmonary arterial hypertension in mice

S Lakhal-Littleton, A Crosby, MC Frise… - Proceedings of the …, 2019 - National Acad Sciences
Iron deficiency augments hypoxic pulmonary arterial pressure in healthy individuals and
exacerbates pulmonary arterial hypertension (PAH) in patients, even without anemia. …

[HTML][HTML] How do antihypertensive drugs work? Insights from studies of the renal regulation of arterial blood pressure

H Digne-Malcolm, MC Frise, KL Dorrington - Frontiers in physiology, 2016 - frontiersin.org
Though antihypertensive drugs have been in use for many decades, the mechanisms by
which they act chronically to reduce blood pressure remain unclear. Over long periods, mean …

A cross-sectional study of the prevalence and associations of iron deficiency in a cohort of patients with chronic obstructive pulmonary disease

AH Nickol, MC Frise, HY Cheng, A McGahey… - BMJ open, 2015 - bmjopen.bmj.com
Objectives Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity
and mortality. Iron deficiency, with or without anaemia, is associated with other chronic …

[HTML][HTML] Intravenous iron to treat anaemia following critical care: a multicentre feasibility randomised trial

…, T James, H Drakesmith, PA Robbins, MC Frise… - British journal of …, 2022 - Elsevier
Background Anaemia is common and associated with poor outcomes in survivors of critical
illness. However, the optimal treatment strategy is unclear. Methods We conducted a …

[HTML][HTML] Abnormal whole-body energy metabolism in iron-deficient humans despite preserved skeletal muscle oxidative phosphorylation

MC Frise, DA Holdsworth, AW Johnson, YJ Chung… - Scientific reports, 2022 - nature.com
Iron deficiency impairs skeletal muscle metabolism. The underlying mechanisms are
incompletely characterised, but animal and human experiments suggest the involvement of …

Intravenous iron and chronic obstructive pulmonary disease: a randomised controlled trial

P Santer, A McGahey, MC Frise… - BMJ open …, 2020 - bmjopenrespres.bmj.com
Background Increased iron availability modifies cardiorespiratory function in healthy
volunteers and improves exercise capacity and quality of life in patients with heart failure or …