TriTrypDB ( http://tritrypdb.org ) is an integrated database providing access to genome-scale
datasets for kinetoplastid parasites, and supporting a variety of complex queries driven by …

Leishmania parasites cause a spectrum of clinical pathology in humans ranging from
disfiguring cutaneous lesions to fatal visceral leishmaniasis. We have generated a reference …

Sand flies are the exclusive vectors of the protozoan parasite Leishmania 1 , but the mechanism
of transmission by fly bite has not been determined nor incorporated into experimental …

The life cycle of Leishmania alternates between two main morphological forms: intracellular
amastigotes in the mammalian host and motile promastigotes in the sand fly vector. Several …

Transmission of leishmaniasis is effected by a specific developmental stage, the metacyclic
promastigote. The precursors of metacyclic promastigotes were a distinct subpopulation of …

GeneDB ( http://www.genedb.org ) is a genome database for prokaryotic and eukaryotic
pathogens and closely related organisms. The resource provides a portal to genome sequence …

Leishmania alternates between two main morphological forms in its life cycle: intracellular
amastigotes in the mammalian host and motile promastigotes in the sandfly vector. Several …

In nature the prevalence of Leishmania infection in whole sand fly populations can be very
low (<0.1%), even in areas of endemicity and high transmission. It has long since been …

Chlorarachniophytes are amoeboflagellate algae that acquired photosynthesis secondarily
by engulfing a green alga and retaining its plastid (chloroplast). An important consequence …

Neonates are protected from colonizing bacteria by antibodies secreted into maternal milk.
Necrotizing enterocolitis (NEC) is a disease of neonatal preterm infants with high morbidity …