[HTML][HTML] Microbiome definition re-visited: old concepts and new challenges
The field of microbiome research has evolved rapidly over the past few decades and has
become a topic of great scientific and public interest. As a result of this rapid growth in interest …
become a topic of great scientific and public interest. As a result of this rapid growth in interest …
Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
Plasticity of the cell state has been proposed to drive resistance to multiple classes of cancer
therapies, thereby limiting their effectiveness 1 , 2 , 3 , 4 . A high-mesenchymal cell state …
therapies, thereby limiting their effectiveness 1 , 2 , 3 , 4 . A high-mesenchymal cell state …
Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
MJ Hangauer, VS Viswanathan, MJ Ryan, D Bole… - Nature, 2017 - nature.com
Acquired drug resistance prevents cancer therapies from achieving stable and complete
responses 1 . Emerging evidence implicates a key role for non-mutational drug resistance …
responses 1 . Emerging evidence implicates a key role for non-mutational drug resistance …
[HTML][HTML] Percutaneous revascularization for ischemic left ventricular dysfunction
…, JP Greenwood, R Weerackody, M Ryan… - … England Journal of …, 2022 - Mass Medical Soc
Background Whether revascularization by percutaneous coronary intervention (PCI) can
improve event-free survival and left ventricular function in patients with severe ischemic left …
improve event-free survival and left ventricular function in patients with severe ischemic left …
Organocatalyzed atom transfer radical polymerization driven by visible light
Atom transfer radical polymerization (ATRP) has become one of the most implemented
methods for polymer synthesis, owing to impressive control over polymer composition and …
methods for polymer synthesis, owing to impressive control over polymer composition and …
A framework for evaluating ecosystem services provided by cover crops in agroecosystems
Cropping systems that provide ecosystem services beyond crop production are gaining interest
from farmers, policy makers and society at large, yet we lack frameworks to evaluate and …
from farmers, policy makers and society at large, yet we lack frameworks to evaluate and …
International consensus statement on allergy and rhinology: allergic rhinitis
…, C Rondon, L Rudmik, M Ryan… - International forum of …, 2018 - Wiley Online Library
Background Critical examination of the quality and validity of available allergic rhinitis (AR)
literature is necessary to improve understanding and to appropriately translate this …
literature is necessary to improve understanding and to appropriately translate this …
Navigating a critical juncture for sustainable weed management
Agricultural weed management has become entrenched in a single tactic—herbicide-resistant
crops—and needs greater emphasis on integrated practices that are sustainable over the …
crops—and needs greater emphasis on integrated practices that are sustainable over the …
International consensus statement on allergy and rhinology: Allergic rhinitis–2023
…, CS Rhee, S Reitsma, M Ryan… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …
Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles
…, D Moosmayer, A Hilpmann, MJ Ryan… - Nature chemical …, 2020 - nature.com
We recently described glutathione peroxidase 4 (GPX4) as a promising target for killing
therapy-resistant cancer cells via ferroptosis. The onset of therapy resistance by multiple types of …
therapy-resistant cancer cells via ferroptosis. The onset of therapy resistance by multiple types of …