The outcome of herpes simplex virus (HSV) encephalitis is improved with prompt initiation
of aciclovir treatment. Delays are common, but there is little understanding of why they occur. …

Background: Critically ill patients are at high risk for acquiring Clostridium difficile infection.
The aim of this study was to investigate the prevalence, severity, and outcome of …

Some countries have been particularly successful in controlling MRSA. Notable is the
experience of the Netherlands. The Dutch strategy has been based on a policy of ‘search and …

Recognition of Clostridium difficile began in the early 1970s with a few isolated reports of a
severe, even lethal, colitis. Because of its frequent association with exposure to a specific …

In the 1980s the outcome of patients with herpes simplex encephalitis was shown to be
dramatically improved with aciclovir treatment. Delays in starting treatment, particularly beyond …

In the 1980s the outcome of patients with herpes simplex encephalitis was shown to be
dramatically improved with aciclovir treatment. Delays in starting treatment, particularly beyond …

Background: Over the last 15 years, bacterial meningitis has received considerable attention,
including national guidelines, whilst viral central nervous system (CNS) infections have …

Background Identification and tracking of important communicable diseases is pivotal to our
understanding of the geographical distribution of disease, the emergence and spread of …

Objective Thanks to the introduction of recent national guidelines for treating herpes simplex
virus (HSV) encephalitis health outcomes have improved. This paper evaluates the costs …

Objective To determine whether a tailored multifaceted implementation strategy improves
the initial management of patients with suspected encephalitis. Design Pragmatic two arm …