Bronchiectasis in adults is a chronic disorder associated with poor quality of life and frequent
exacerbations in many patients. There have been no previous international guidelines. The …

CT scanning can also aid in identifying an aetiology of bronchiectasis eg Allergic
bronchopulmonary aspergillosis (ABPA), Non-tuberculous mycobacteria (NTM), primary ciliary …

By moving essential body fluids and molecules, motile cilia and flagella govern respiratory
mucociliary clearance, laterality determination and the transport of gametes and …

Primary ciliary dyskinesia (PCD) in adults has not been well described. In this retrospective
observational study we aimed to characterise a large adult population and identify features …

Background Patients with bronchiectasis have frequent exacerbations that are thought to be
related to neutrophilic inflammation. The activity and quantity of neutrophil serine proteases, …

Background Since the publication of the British Thoracic Society (BTS) Guideline on the ‘Management
of opportunistic mycobacterial infections’ in 2000, our understanding of the …

Cancer is a leading cause of mortality throughout the world and new treatments are urgently
needed. Recent studies suggest that bone marrow–derived mesenchymal stem cells (MSC) …

There is a need for a clear definition of exacerbations used in clinical trials in patients with
bronchiectasis. An expert conference was convened to develop a consensus definition of an …

Rationale: Improved therapeutic options are needed for patients with treatment-refractory
nontuberculous mycobacterial lung disease caused by Mycobacterium avium complex (MAC). …

The ability of mesenchymal stem cells (MSC) to specifically home to tumors has suggested
their potential use as a delivery vehicle for cancer therapeutics. MSC integration into tumors …