[HTML][HTML] Identification of late-onset hypogonadism in middle-aged and elderly men

…, TS Han, K Kula, MEJ Lean, N Pendleton… - … England Journal of …, 2010 - Mass Medical Soc
Background The association between aging-related testosterone deficiency and late-onset
hypogonadism in men remains a controversial concept. We sought evidence-based criteria …

[HTML][HTML] Physical activity in older age: perspectives for healthy ageing and frailty

…, DP French, D Jackson, J Nazroo, N Pendleton… - Biogerontology, 2016 - Springer
Regular physical activity helps to improve physical and mental functions as well as reverse
some effects of chronic disease to keep older people mobile and independent. Despite the …

Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence

…, AC Need, W Ollier, A Palotie, A Payton, N Pendleton… - Nature …, 2018 - nature.com
Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

Genome-wide association studies establish that human intelligence is highly heritable and polygenic

…, DJ Porteous, M Horan, JM Starr, N Pendleton… - Molecular …, 2011 - nature.com
General intelligence is an important human quantitative trait that accounts for much of the
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …

Characteristics of secondary, primary, and compensated hypogonadism in aging men: evidence from the European Male Ageing Study

…, F Labrie, MEJ Lean, N Pendleton… - The Journal of …, 2010 - academic.oup.com
Context: The diagnosis of late-onset hypogonadism (LOH) in older men with age-related
declines in testosterone (T) is currently not well characterized. Objective: Our objective was to …

Genome-wide association meta-analysis of 78,308 individuals identifies new loci and genes influencing human intelligence

…, MB Miller, WER Ollier, A Payton, N Pendleton… - Nature …, 2017 - nature.com
Intelligence is associated with important economic and health-related life outcomes 1.
Despite intelligence having substantial heritability 2 (0.54) and a confirmed polygenic nature, …

Age-related changes in general and sexual health in middle-aged and older men: results from the European Male Ageing Study (EMAS)

…, M Maggi, TW O'Neill, N Pendleton… - The journal of sexual …, 2010 - academic.oup.com
Introduction Limited information is available concerning the general and sexual health status
of European men. Aim To investigate the age-related changes in general and sexual health …

Sexual health and well-being among older men and women in England: Findings from the English Longitudinal Study of Ageing

…, J Nazroo, DB O'Connor, M Blake, N Pendleton - Archives of sexual …, 2016 - Springer
We describe levels of sexual activity, problems with sexual functioning, and concerns about
sexual health among older adults in the English Longitudinal Study of Ageing (ELSA), and …

Characteristics of androgen deficiency in late-onset hypogonadism: results from the European Male Aging Study (EMAS)

…, F Labrie, MEJ Lean, N Pendleton… - The Journal of …, 2012 - academic.oup.com
Context: Late-onset hypogonadism (LOH) has been defined as a syndrome in middle-aged
and elderly men reporting symptoms in the presence of low testosterone (T). Objective: The …

[HTML][HTML] GWAS meta-analysis reveals novel loci and genetic correlates for general cognitive function: a report from the COGENT consortium

…, M Gill, AR Hariri, DR Weinberger, N Pendleton… - Molecular …, 2017 - nature.com
The complex nature of human cognition has resulted in cognitive genomics lagging behind
many other fields in terms of gene discovery using genome-wide association study (GWAS) …