[HTML][HTML] Rapid whole-genome sequencing for investigation of a neonatal MRSA outbreak

…, MJ Ellington, EJP Cartwright, NM Brown… - … England Journal of …, 2012 - Mass Medical Soc
Background Isolates of methicillin-resistant Staphylococcus aureus (MRSA) belonging to a
single lineage are often indistinguishable by means of current typing techniques. Whole-…

[PDF][PDF] Spondylodiscitis: update on diagnosis and management

T Gouliouris, SH Aliyu, NM Brown - Journal of Antimicrobial …, 2010 - academia.edu
Spondylodiscitis, a term encompassing vertebral osteomyelitis, spondylitis and discitis, is
the main manifestation of haematogenous osteomyelitis in patients aged over 50 years. …

[HTML][HTML] Whole-genome sequencing for analysis of an outbreak of meticillin-resistant Staphylococcus aureus: a descriptive study

…, ME Török, MTG Holden, NM Brown… - The Lancet infectious …, 2013 - thelancet.com
Background The emergence of meticillin-resistant Staphylococcus aureus (MRSA) that can
persist in the community and replace existing hospital-adapted lineages of MRSA means that …

[HTML][HTML] Routine use of microbial whole genome sequencing in diagnostic and public health microbiology

…, EJP Cartwright, SH Gillespie, NM Brown, M Farrington… - 2012 - journals.plos.org
Whole genome sequencing (WGS) promises to be transformative for the practice of clinical
microbiology, and the rapidly falling cost and turnaround time mean that this will become a …

Derivation of androgen‐independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells

…, JT Hsieh, ME Gleave, NM Brown… - … journal of cancer, 1994 - Wiley Online Library
A model of human prostate cancer was established to study cellular interaction between
prostate cancer and bone stroma in vivo. In this model, subcutaneous co‐injection of 2 non‐…

[HTML][HTML] Ventilator-associated pneumonia in critically ill patients with COVID-19

…, A Soderholm, S Forrest, S Sridhar, NM Brown… - Critical Care, 2021 - Springer
Background Pandemic COVID-19 caused by the coronavirus SARS-CoV-2 has a high
incidence of patients with severe acute respiratory syndrome (SARS). Many of these patients …

Total knee arthroplasty has higher postoperative morbidity than unicompartmental knee arthroplasty: a multicenter analysis

NM Brown, NP Sheth, K Davis, ME Berend… - The Journal of …, 2012 - Elsevier
A total of 2235 primary total knee arthroplasties (TKAs) and 605 unicompartmental knee
arthroplasties performed at 3 institutions over 5 years were reviewed to compare the incidence …

Dilute betadine lavage before closure for the prevention of acute postoperative deep periprosthetic joint infection

NM Brown, CA Cipriano, M Moric, SM Sporer… - The Journal of …, 2012 - Elsevier
This study evaluated the efficacy of a dilute Betadine (Purdue Pharma, Stamford, Conn)
lavage in preventing early deep postoperative infection after total hip (THA) and knee (TKA) …

Systematic longitudinal survey of invasive Escherichia coli in England demonstrates a stable population structure only transiently disturbed by the emergence of …

…, SR Harris, J Corander, NM Brown… - Genome …, 2017 - genome.cshlp.org
Escherichia coli associated with urinary tract infections and bacteremia has been intensively
investigated, including recent work focusing on the virulent, globally disseminated, multidrug…

Rapid bacterial whole-genome sequencing to enhance diagnostic and public health microbiology

…, NM Brown, MTG Holden, M Quail… - JAMA internal …, 2013 - jamanetwork.com
Importance The latest generation of benchtop DNA sequencing platforms can provide an
accurate whole-genome sequence (WGS) for a broad range of bacteria in less than a day. …