Background Enhanced Recovery After Surgery (ERAS) protocols reduce length of stay,
complications and costs for a large number of elective surgical procedures. A similar, structured …

Objective: To determine factors which influence the outcome of surgical techniques to close
enterocutaneous fistulas within the open abdomen. Summary Background Data: …

Background This is Part 2 of the first consensus guidelines for optimal care of patients
undergoing emergency laparotomy (EL) using an Enhanced Recovery After Surgery (ERAS) …

The frailty syndrome is defined as a decrease in physiological reserve across multiple organ
systems leading to increased vulnerability to external stressors. Studies across surgical …

O 6 -Methylguanine (O 6 -MeG), a procarcinogenic DNA adduct that arises from exposure to
methylating agents, has been detected in human colorectal DNA at levels comparable to …

N7-Methyldeoxyguanosine (N7-MedG) in DNA is a biomarker of exposure to environmental
and endogenous methylating agents and may be of use in epidemiological studies. To …

Components of human diets may influence the incidence of colorectal adenomas, by
modifying exposure or susceptibility to DNA-damaging alkylating agents. To examine this …

There is increasing evidence to suggest that O 6 -alkyl guanine DNA-alkyltransferase (MGMT)
activity provides protection against alkylating agent induced formation of GC→AT …

Background and aims:O 6 -alkylguanine DNA-alkyltransferase (MGMT) provides protection
against alkylating agent-induced GC→AT transition mutations. Such mutations are frequently …

… Critical revision of the manuscript for important intellectual content: Mattias Soop, Nicholas
P. Lees, Iain D. Anderson and Simon Lal. Statistical analysis: Ramya Kalaiselvan and Gordon …