Background Regular physical activity is the prime modality for the prevention of numerous
non-communicable diseases and has also been advocated for resilience against COVID-19 …

The Aurora kinases have been the subject of considerable interest as targets for the development
of new anticancer agents. While evidence suggests inhibition of Aurora B kinase gives …

Tobacco smoke is the leading cause of preventable premature death worldwide. While the
majority of smokers would like to stop, the habitual and addictive nature of smoking makes …

If patients are to participate fully in their care and in the management of a long term condition
such as chronic obstructive pulmonary disease, good communication is essential. However…

Background Our aims were to evaluate critically the evidence from systematic reviews as well
as narrative reviews of the effects of melatonin (MLT) on health and to identify the potential …

A novel series of 5-aminopyrimidinyl quinazolines has been developed from anilino-quinazoline
1, which was identified in a high throughput screen for Aurora A. Introduction of the …

Background Guidelines recommend implementation of multimodal interventions to help
prevent recurrent TIA/stroke. We undertook a systematic review to assess the effectiveness of …

The relationship between the upper and lower airways in chronic obstructive pulmonary
disease (COPD) is unknown. We examined the prevalence of chronic nasal symptoms and the …

Background Chronic obstructive pulmonary disease (COPD) is a chronic, progressive
disease and is treated with inhaled medication to optimize the patient’s lung health through …

Background Nurses have been at the forefront of the pandemic response, involved in
extensive coordination of services, screening, vaccination and front-line work in respiratory, …