Background Reliable data on the prevalence and predictors of post-stroke dementia are
needed to inform patients and carers, plan services and clinical trials, ascertain the overall …

Objective: To study the early risk of recurrent stroke by etiologic subtype. Methods: The authors
studied risk of recurrent stroke by etiologic subtype (Trial of ORG 10172 in Acute Stroke …

Background Stroke is often preceded by transient ischaemic attack (TIA), but studies of stroke
risk after TIA are logistically difficult and have yielded conflicting results. However, reliable …

In making treatment decisions, doctors and patients must take into account relevant randomised
controlled trials (RCTs) and systematic reviews. Relevance depends on external validity …

Background Carotid endarterectomy reduces the risk of stroke in patients with recently
symptomatic stenosis. Benefit depends on the degree of stenosis, and we aimed to see whether it …

Background The mechanisms by which hypertension causes vascular events are unclear.
Guidelines for diagnosis and treatment focus only on underlying mean blood pressure. We …

Background We aimed to validate two similar existing prognostic scores for early risk of stroke
after transient ischaemic attack (TIA) and to derive and validate a unified score optimised …

Background Treatment with daily aspirin for 5 years or longer reduces subsequent risk of
colorectal cancer. Several lines of evidence suggest that aspirin might also reduce risk of other …

… Peter M Rothwell, MD Peter M Rothwell … Hôpital L Pasteur, Colmar, France (1): G Rodier,
E Cohen, E Baldauf, PM Schatz, MH Dugay-Arentz, F Vuillemet, B Stilhart, R Srour, C Bizette, A …

Background Endarterectomy reduces risk of stroke in certain patients with recently symptomatic
internal carotid stenosis. However, investigators have made different recommendations …