Reduced cellularity of bone marrow in multiple sclerosis with decreased MSC expansion potential and premature ageing in vitro

J Redondo, P Sarkar, K Kemp, PF Virgo… - Multiple Sclerosis …, 2018 - journals.sagepub.com
Background: Autologous bone-marrow-derived cells are currently employed in clinical
studies of cell-based therapy in multiple sclerosis (MS) although the bone marrow …

[HTML][HTML] Percutaneous endoscopic gastrostomy tube insertion in neurodegenerative disease: a retrospective study and literature review

P Sarkar, A Cole, NJ Scolding, CM Rice - Clinical endoscopy, 2017 - ncbi.nlm.nih.gov
Methods A retrospective case note review of patients referred for PEG insertion by neurologists
in a single neuroscience center was conducted according to a pre-determined set of …

Dysregulation of mesenchymal stromal cell antioxidant responses in progressive multiple sclerosis

J Redondo, P Sarkar, K Kemp… - Stem Cells …, 2018 - academic.oup.com
The potential of autologous cell-based therapies including those using multipotent
mesenchymal stromal cells (MSCs) is being investigated for multiple sclerosis (MS) and other …

[HTML][HTML] Assessment of bone marrow-derived Cellular Therapy in progressive Multiple Sclerosis (ACTiMuS): study protocol for a randomised controlled trial

…, MG Guttridge, G Miflin, S Blackmore, P Sarkar… - Trials, 2015 - Springer
Background We have recently completed an evaluation of the safety and feasibility of intravenous
delivery of autologous bone marrow in patients with progressive multiple sclerosis (MS…

[HTML][HTML] Reduced neuroprotective potential of the mesenchymal stromal cell secretome with ex vivo expansion, age and progressive multiple sclerosis

P Sarkar, J Redondo, K Kemp, M Ginty, A Wilkins… - Cytotherapy, 2018 - Elsevier
Background Clinical trials using ex vivo expansion of autologous mesenchymal stromal
cells (MSCs) are in progress for several neurological diseases including multiple sclerosis (MS). …

Cell therapy for multiple sclerosis

P Sarkar, CM Rice, NJ Scolding - CNS drugs, 2017 - Springer
Cell therapy is considered a promising potential treatment for multiple sclerosis, perhaps
particularly for the progressive form of the disease for which there are currently no useful …

Peer mentoring for core medical trainees: uptake and impact

J Webb, A Brightwell, P Sarkar, R Rabbie… - Postgraduate …, 2015 - academic.oup.com
Objective To assess the uptake and impact of a peer mentoring scheme for core medical
trainees on both mentors and mentees. Method All second year core medical trainees in the …

Repeat infusion of autologous bone marrow cells in multiple sclerosis: protocol for a phase I extension study (SIAMMS-II)

…, NM Kane, MG Guttridge, J Redondo, P Sarkar… - BMJ open, 2015 - bmjopen.bmj.com
Introduction The ‘Study of Intravenous Autologous Marrow in Multiple Sclerosis (SIAMMS)’
trial was a safety and feasibility study which examined the effect of intravenous infusion of …

Transverse myelitis caused by hepatitis E: previously undescribed in adults

P Sarkar, C Morgan, S Ijaz - Case Reports, 2015 - casereports.bmj.com
We report the case of a 62-year-old Caucasian woman who was admitted with urinary
retention and lower limb paraesthesia following a week9s prodromal illness of headache and …

Reduced expression of mitochondrial fumarate hydratase in progressive multiple sclerosis contributes to impaired in vitro mesenchymal stromal cell-mediated …

P Sarkar, J Redondo, K Hares, S Bailey… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Cell-based therapies for multiple sclerosis (MS), including those employing
autologous bone marrow-derived mesenchymal stromal cells (MSC) are being examined in …