Practical problems in the respiratory care of patients with muscular dystrophy
PEM Smith, PMA Calverley… - … England Journal of …, 1987 - Mass Medical Soc
THE muscular dystrophies comprise several groups of inherited disorders with a wide
variation between the groups in the distribution and severity of muscle involvement. The …
variation between the groups in the distribution and severity of muscle involvement. The …
The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial
Background Valproate is widely accepted as a drug of first choice for patients with generalised
onset seizures, and its broad spectrum of efficacy means it is recommended for patients …
onset seizures, and its broad spectrum of efficacy means it is recommended for patients …
The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded …
Background Carbamazepine is widely accepted as a drug of first choice for patients with
partial onset seizures. Several newer drugs possess efficacy against these seizure types but …
partial onset seizures. Several newer drugs possess efficacy against these seizure types but …
Electrocardiographic accompaniments of temporal lobe epileptic seizures
LD Blumhardt, PEM Smith, L Owen - The Lancet, 1986 - Elsevier
74 spontaneous seizures in 26 patients with a clinical diagnosis of temporal lobe epilepsy (complex
partial seizures) were recorded by simultaneous ambulatory cassette monitoring of …
partial seizures) were recorded by simultaneous ambulatory cassette monitoring of …
Initial management of seizure in adults
PEM Smith - New England Journal of Medicine, 2021 - Mass Medical Soc
Key Clinical Points Initial Management of Seizure in Adults The clinical diagnosis of an
epileptic seizure requires a detailed history taking and, ideally, an eyewitness account of the …
epileptic seizure requires a detailed history taking and, ideally, an eyewitness account of the …
Self‐discontinuation of antiepileptic medication in pregnancy: detection by hair analysis
Purpose: Concerns over teratogenicity of antiepileptic drugs (AEDs) during pregnancy must
be balanced against the risks of seizures to the mother and developing fetus. …
be balanced against the risks of seizures to the mother and developing fetus. …
Patients with epilepsy: cognitively compromised before the start of antiepileptic drug treatment?
Purpose: To compare the cognitive profile of newly diagnosed untreated epilepsy patients
with healthy volunteers using a comprehensive neuropsychological test battery. Methods: A …
with healthy volunteers using a comprehensive neuropsychological test battery. Methods: A …
Hypoxemia during sleep in Duchenne muscular dystrophy.
PEM Smith, PMA Calverley… - American Journal of …, 1988 - atsjournals.org
Duchenne muscular dystrophy is an X-linked recessive disorder manifesting as a chronic
progressive decline in skeletal and respiratory muscle function from early childhood. Daytime …
progressive decline in skeletal and respiratory muscle function from early childhood. Daytime …
Adjunctive therapy versus alternative monotherapy in patients with partial epilepsy failing on a single drug: a multicentre, randomised, pragmatic controlled trial
…, DW Chadwick, M Nikanorova, SA Gromov, PEM Smith… - Epilepsy research, 2003 - Elsevier
Objective: To evaluate the value of alternative monotherapy versus adjunctive therapy in
partial epilepsy refractory to single antiepileptic drug (AED) therapy. Design and methods: In a …
partial epilepsy refractory to single antiepileptic drug (AED) therapy. Design and methods: In a …
Ventilation and breathing pattern during sleep in Duchenne muscular dystrophy
PEM Smith, RHT Edwards, PMA Calverley - Chest, 1989 - Elsevier
Ventilatory data, including timing and partitioning of ventilation, were obtained from six
subjects with advanced Duchenne muscular dystrophy, aged 16 to 22 years, during …
subjects with advanced Duchenne muscular dystrophy, aged 16 to 22 years, during …