User profiles for Phil EM Smith
Phil SmithConsultant Neurologist Verified email at cf.ac.uk Cited by 10905 |
The SANAD study of effectiveness of valproate, lamotrigine, or topiramate for generalised and unclassifiable epilepsy: an unblinded randomised controlled trial
Background Valproate is widely accepted as a drug of first choice for patients with generalised
onset seizures, and its broad spectrum of efficacy means it is recommended for patients …
onset seizures, and its broad spectrum of efficacy means it is recommended for patients …
The SANAD study of effectiveness of carbamazepine, gabapentin, lamotrigine, oxcarbazepine, or topiramate for treatment of partial epilepsy: an unblinded …
Background Carbamazepine is widely accepted as a drug of first choice for patients with
partial onset seizures. Several newer drugs possess efficacy against these seizure types but …
partial onset seizures. Several newer drugs possess efficacy against these seizure types but …
Initial management of seizure in adults
PEM Smith - New England Journal of Medicine, 2021 - Mass Medical Soc
Key Clinical Points Initial Management of Seizure in Adults The clinical diagnosis of an
epileptic seizure requires a detailed history taking and, ideally, an eyewitness account of the …
epileptic seizure requires a detailed history taking and, ideally, an eyewitness account of the …
Self‐discontinuation of antiepileptic medication in pregnancy: detection by hair analysis
Purpose: Concerns over teratogenicity of antiepileptic drugs (AEDs) during pregnancy must
be balanced against the risks of seizures to the mother and developing fetus. …
be balanced against the risks of seizures to the mother and developing fetus. …
Epilepsy in the elderly
A Johnston, PEM Smith - Expert review of neurotherapeutics, 2010 - Taylor & Francis
… Phil EM Smith has received research funding and teaching honoraria and travel grants
from UCB Pharma, Eisai and Janssen-Cilag Pharmaceuticals. The authors have no other …
from UCB Pharma, Eisai and Janssen-Cilag Pharmaceuticals. The authors have no other …
Epilepsy and deprivation, a data linkage study
Objective To investigate whether the link between epilepsy and deprivation is due to factors
associated with deprivation (social causation) or factors associated with a diagnosis of …
associated with deprivation (social causation) or factors associated with a diagnosis of …
[HTML][HTML] Validating epilepsy diagnoses in routinely collected data
…, HWR Powell, IMS Sawhney, RA Lyons, PEM Smith… - Seizure, 2017 - Elsevier
Purpose Anonymised, routinely-collected healthcare data is increasingly being used for
epilepsy research. We validated algorithms using general practitioner (GP) primary healthcare …
epilepsy research. We validated algorithms using general practitioner (GP) primary healthcare …
[HTML][HTML] Trends in the first antiepileptic drug prescribed for epilepsy between 2000 and 2010
Purpose To investigate changes in the choice of first anti-epileptic drug (AED) and co-prescription
of folic acid after a new diagnosis of epilepsy. Methods We searched anonymised …
of folic acid after a new diagnosis of epilepsy. Methods We searched anonymised …
[HTML][HTML] Epilepsy in Rett syndrome: association between phenotype and genotype, and implications for practice
B Cardoza, A Clarke, J Wilcox, F Gibbon, PEM Smith… - Seizure, 2011 - Elsevier
PURPOSE: To investigate the association between genotype (methyl-CpG-binding protein
2 (MECP2 gene mutation)) and epileptic seizure phenotype in Rett syndrome. METHODS: …
2 (MECP2 gene mutation)) and epileptic seizure phenotype in Rett syndrome. METHODS: …
Progressive mitochondrial disease resulting from a novel missense mutation in the mitochondrial DNA ND3 gene
…, R Singh‐Kler, CM Hayes, PEM Smith… - Annals of Neurology …, 2001 - Wiley Online Library
We describe a 42‐year‐old man who presented with a progressive history of epilepsy,
stroke‐like episodes, bilateral optic atrophy, and cognitive decline. Investigation of his muscle …
stroke‐like episodes, bilateral optic atrophy, and cognitive decline. Investigation of his muscle …