Background Results of small trials indicate that fluoxetine might improve functional outcomes
after stroke. The FOCUS trial aimed to provide a precise estimate of these effects. Methods …

Importance Hypoxia is common in the first few days after acute stroke, is frequently intermittent,
and is often undetected. Oxygen supplementation could prevent hypoxia and secondary …

Background A new syndrome of vaccine-induced immune thrombotic thrombocytopenia (VITT)
has emerged as a rare side-effect of vaccination against COVID-19. Cerebral venous …

Objective We set out to determine which characteristics and outcomes of stroke are associated
with COVID-19. Methods This case-control study included patients admitted with stroke to …

Background Hypoxia is a common occurrence following stroke and associated with poor
clinical and functional outcomes. Normal oxygen physiology is a finely controlled mechanism …

Importance Cryptogenic strokes constitute approximately 40% of ischemic strokes in young
adults, and most meet criteria for the embolic stroke of undetermined source (ESUS). Two …

Objectives We examined the association between obesity and early-onset cryptogenic
ischemic stroke (CIS) and whether fat distribution or sex altered this association. Materials and …

The majority of people who suffer a stroke are older adults. The last two decades have brought
major progress in the diagnosis and management of stroke, which has led to significant …

Hospital can be a very frightening place for patients. As clinicians we can become complacent
to the trepidation that some patients face on a daily basis as we move from patient to …

Background Mechanical thrombectomy was approved by NICE as a treatment for stroke in
2016. However, most of the evidence is from studies conducted during working hours. Only …