User profiles for Piers EM Patten

Piers Patten

Clinical Senior Lecturer, King's College London
Verified email at kcl.ac.uk
Cited by 4217

Tisagenlecleucel in adult relapsed or refractory follicular lymphoma: the phase 2 ELARA trial

…, AJM Ferreri, T Teshima, PEM Patten… - Nature medicine, 2022 - nature.com
Tisagenlecleucel is an autologous anti-CD19 chimeric antigen receptor-T cell therapy with
clinically meaningful outcomes demonstrated in patients with relapsed/refractory (r/r) B-cell …

[HTML][HTML] Targeting the tumor microenvironment in chronic lymphocytic leukemia

R Svanberg, S Janum, PEM Patten, AG Ramsay… - …, 2021 - ncbi.nlm.nih.gov
The tumor microenvironment (TME) plays an essential role in the development, growth, and
survival of the malignant B-cell clone in chronic lymphocytic leukemia (CLL). Within the …

Outcomes of COVID-19 in patients with CLL: a multicenter international experience

…, H Parry, MR Wilson, PEM Patten… - Blood, The Journal …, 2020 - ashpublications.org
Given advanced age, comorbidities, and immune dysfunction, chronic lymphocytic leukemia
(CLL) patients may be at particularly high risk of infection and poor outcomes related to …

CD38 expression in chronic lymphocytic leukemia is regulated by the tumor microenvironment

PEM Patten, AGS Buggins, J Richards… - Blood, The Journal …, 2008 - ashpublications.org
Chronic lymphocytic leukemia (CLL) is a lymphoproliferative disease with a highly variable
outcome. The prognosis of patients with CLL may be predicted using a number of biomarkers…

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease

…, C Calissano, S Marsilio, PEM Patten… - Blood, The Journal …, 2011 - ashpublications.org
Chronic lymphocytic leukemia (CLL) is an incurable adult disease of unknown etiology.
Understanding the biology of CLL cells, particularly cell maturation and growth in vivo, has been …

[HTML][HTML] Immunogenicity of SARS-CoV-2 vaccines in patients with cancer

H Kakkassery, E Carpenter, PEM Patten… - Trends in Molecular …, 2022 - cell.com
Transmission of the SARS-CoV-2 virus and its corresponding disease (COVID-19) has
been shown to impose a higher burden on cancer patients than on the general population. …

[HTML][HTML] Ibrutinib plus venetoclax in relapsed/refractory chronic lymphocytic leukemia: the CLARITY study

…, A Pettitt, JG Gribben, PEM Patten… - Journal of clinical …, 2019 - ncbi.nlm.nih.gov
PURPOSE The treatment of chronic lymphocytic leukemia (CLL) has been revolutionized by
targeted therapies that either inhibit proliferation (ibrutinib) or reactivate apoptosis (…

Management of cardiovascular complications of Bruton tyrosine kinase inhibitors

…, N Parry‐Jones, PEM Patten… - British journal of …, 2022 - Wiley Online Library
1Oxford University Hospitals NHS Trust, Oxford, 2Liverpool Centre for Cardiovascular
Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK, …

Chronic lymphocytic leukemia therapy guided by measurable residual disease

…, R de Tute, A Rawstron, PEM Patten… - … England Journal of …, 2024 - Mass Medical Soc
… Rawstron, PEM Patten, and P. Hillmen, for the National Cancer Research Institute Chronic
Lymphocytic Leukemia … D., Piers EM Patten, Ph.D., FRCP, and Peter Hillmen, MB, Ch.B., Ph.…

[PDF][PDF] Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients

…, A Rigg, S Papa, AC Hayday, PEM Patten… - Cancer cell, 2021 - cell.com
Given the immune system's importance for cancer surveillance and treatment, we have
investigated how it may be affected by SARS-CoV-2 infection of cancer patients. Across some …