[HTML][HTML] 40 years of CSF toxicity studies in ALS: What have we learnt about ALS pathophysiology?

KC Ng Kee Kwong, PK Harbham… - Frontiers in Molecular …, 2021 - frontiersin.org
Based on early evidence of in vitro neurotoxicity following exposure to serum derived from
patients with amyotrophic lateral sclerosis (ALS), several studies have attempted to explore …

Review of orthopaedic trauma surgery during the peak of COVID-19 pandemic–An observational cohort study in the UK

C De, N Kainth, PK Harbham, M Brooks… - Journal of Clinical …, 2021 - Elsevier
Aim This study aims to estimate the risk of acquiring medical complication or death from
COVID-19 infection in patients who were admitted for orthopaedic trauma surgery during the …

OUTCOME OF ORTHOPAEDIC TRAUMA SURGERIES DURING THE PEAK AND PLATEAU OF COVID-19 PANDEMIC: AN ASSESSMENT OF MARGIN OF SAFETY

C De, N Kainth, P Harbham, M Brooks… - Orthopaedic …, 2022 - boneandjoint.org.uk
Background This study aims to estimate the risk of acquiring a medical complication or death
from COVID-19 infection in patients who were admitted for orthopaedic trauma surgery …

The management of influenza and its complications within the Guy's and St Thomas' NHS Foundation Trust

A Hussain, P Harbham - Clinical Medicine, 2020 - ncbi.nlm.nih.gov
Background The peak number of admissions to hospital intensive care unit (ICU) for
influenza-related complications was higher during the 2015/16 flu season than previous seasons. 1 …

Improving compliance to controlled drug prescription guidelines through the introduction of an EMIS template

P Harbham, A Hussain, D Nair, A Kutty - Future Healthcare Journal, 2020 - ncbi.nlm.nih.gov
Materials and methods In September 2018 baseline data from all patients issued a controlled
drug prescription in the previous 2 months were collected, capturing demographic data …

Improving Pediatric Sepsis Treatment Using a Novel, Guideline-Based Pro Forma

A Hussain, P Harbham, M Zeina - American Journal of Medical …, 2019 - journals.lww.com
UK sepsis guidelines state that patients given oxygen, antibiotics, and intravenous fluids
within 1 hour of querying sepsis reduces sepsis-related mortality by 50%. 1, 2 We introduced a …

An initiative to decrease time to antibiotics for patients with fever and neutropenia

BL Emerson, S Prozora, A Jacob… - American Journal of …, 2019 - journals.sagepub.com
The objective was to decrease the time to antibiotic administration for patients arriving in the
pediatric emergency department with fever and neutropenia. A multidisciplinary team was …

Investigation of endoplasmic reticulum stress and protein aggregates in C9ORF72 mutant induced pluripotent stem cell-derived spinal motor neurons

AB Gane - 2018 - era.ed.ac.uk
… Mr Pratap Harbham and Dr Arpan Mehta joined the lab as I was approaching the end of my
MScR. They were involved in the maintenance of neuronal cultures. Through conversation, …

Elevated IL-6 and TNF-α levels in patients with ALS: inflammation or hypoxia?

C Moreau, D Devos, V Brunaud-Danel, L Defebvre… - Neurology, 2005 - AAN Enterprises
Abnormal levels of interleukin (IL)-6 were described in patients with ALS, related to an
inflammatory process. The authors compared IL-6 and tumor necrosis factor α (TNF-α) levels in …

[HTML][HTML] The impact of COVID-19 on the management and outcomes of patients with proximal femoral fractures: a multi-centre study of 580 patients

A Wignall, V Giannoudis, C De, A Jimenez… - Journal of Orthopaedic …, 2021 - Springer
Pratap Harbham, in particular, contributed to the data collection. Professor Pandit is a
National Institute for Health Research (NIHR) Senior Investigator. The views expressed in this …