Background The management of complex orthopedic infections usually includes a prolonged
course of intravenous antibiotic agents. We investigated whether oral antibiotic therapy is …

Background Microbiological characterisation of co-infections and secondary infections in
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …

Background There are thousands of survivors of the 2014 Ebola outbreak in west Africa.
Ebola virus can persist in survivors for months in immune-privileged sites; however, viral …

Background The COVID-19 pandemic has already claimed considerable lives. There are
major concerns in Africa due to existing high prevalence rates for both infectious and non-…

Antimicrobial resistance (AMR) is a high priority across countries as it increases morbidity,
mortality and costs. Concerns with AMR have resulted in multiple initiatives internationally, …

These good practice recommendations for outpatient parenteral antimicrobial therapy (OPAT)
are an update to a previous consensus statement on OPAT in the UK published in 1998. …

Background Concern regarding bacterial co-infection complicating SARS-CoV-2 has created
a challenge for antimicrobial stewardship. Following introduction of national antibiotic …

Background With the growing global problem of antibiotic resistance it is crucial that
clinicians use antibiotics wisely, which largely means following the principles of antimicrobial …

Background: Clostridium difficile-associated diarrhoea (CDAD) is an increasingly common
and life threatening consequence of modern medical practice. Recurrent disease is seen in …

Background Evidence around prevalence of bacterial coinfection and pattern of antibiotic use
in COVID-19 is controversial although high prevalence rates of bacterial coinfection have …