Background: Anaplastic thyroid carcinomas (ATCs) are among the most lethal malignancies,
for which there is no effective treatment. Objective: In the present study, we aimed to …

Background Cross-sectional imaging regularly results in incidental discovery of adrenal
tumours, requiring exclusion of adrenocortical carcinoma (ACC). However, differentiation is …

Context Up to 3% of US and UK populations are prescribed glucocorticoids (GC). Suppression
of the hypothalamo–pituitary–adrenal axis with the potential risk of adrenal crisis is a …

Objective Beneficial effects of adrenalectomy on cardiovascular risk factors in patients with
subclinical Cushing's syndrome (SCS) are uncertain. We sought to conduct a systematic …

Objective Craniopharyngioma (CP) is a benign tumour of the suprasellar region that is
associated with increased morbidity and mortality in comparison with other causes of …

There has been increasing recognition of the association between various pregnancy
complications and development of chronic disease in later life. Pregnancy has come to be …

Background The process of informed consent for enrolment to a clinical research study can
be complex for both participants and research staff. Challenges include respecting the …

Objectives To report the impact of burosumab on patient-reported outcomes (PROs) and
ambulatory function in adults with X-linked hypophosphataemia (XLH) through 96 weeks. …

An increase in serum osteoprotegerin (OPG) is associated with type 2 diabetes mellitus, the
severity of vascular calcification, and coronary artery disease. Obesity is a risk factor for …

Objectives Since the onset of the COVID-19 pandemic in 2020, there have been plausible
suggestions about the need to augment vitamin D intake by supplementation in order to …