Vascular endothelial growth factor (VEGF) is a crucial pro-angiogenic component in pancreatic
ductal adenocarcinoma (PDA), and its high expression levels have been correlated with …

Cardiac disease complicates 1%–4% of pregnancies globally, with a predominance in low
and middle‐income countries (LMICs). Increasing maternal age, rates of obesity, …

Pancreatic ductal adenocarcinoma (PDA) is a lethal disease with etiological association
with cigarette smoking. Nicotine, an important component of cigarettes, exists at high …

Background Accidental awareness during general anaesthesia (AAGA) is a complex and
rare outcome to investigate in surgical patient populations, particularly obstetric patients. We …

Osteopontin (OPN) is a secreted acidic phosphoprotein that is involved in many inflammatory
and immune-modulating disorders. We previously demonstrated that OPN is a novel islet …

Introduction Although improvement in survival from haematological malignancies has been
reported, a substantial number of these patients develop life threatening complications. …

Central venous access is a vital component of care for critically ill cardiac patients and serves
as a tool for monitoring and delivering vasoactive agents and drugs. The associated risks …

Patients with haematological malignancies (HM) face high rates of intensive care unit (ICU)
admission and mortality. High-flow nasal cannula oxygen (HFNCO) is increasingly used to …

Background Some patients on extracorporeal membrane oxygenation (ECMO) require
prolonged mechanical ventilation. An early tracheostomy strategy while on ECMO has appeared …

Background: Training in simulated environments allows clinicians to practise procedures and
make mistakes without risk to patients. It is important training models offer sufficient fidelity, …