Because depression and painful symptoms commonly occur together, we conducted a literature
review to determine the prevalence of both conditions and the effects of comorbidity on …

Objectives: The objectives of this study were to provide estimates of the prevalence and strength
of association between major depression and chronic pain in a primary care population …

Objective Pain commonly coexists with depression, but its impact on treatment outcomes has
not been well studied. Therefore, we prospectively evaluated the impact of comorbid pain …

A prospective, observational cohort investigation was performed to help understanding the
impact of knee replacement on patients with knee osteoarthritis in community practice. Of …

Atmospheric carbon dioxide concentrations and climate are regulated on geological timescales
by the balance between carbon input from volcanic and metamorphic outgassing and its …

Nitrogen isotopes are an important tool for evaluating past biogeochemical cycling from the
paleoceanographic record. However, bulk sedimentary nitrogen isotope ratios, which can be …

Objective. The literature examining the epidemiology, quality of life burden, cost, and treatment
of diabetic peripheral neuropathy pain (DPNP) in US adults was reviewed. Design. A …

Adolescence represents a critical period of development during which personal lifestyle
choices and behaviour patterns establish, including the choice to be physically active. Physical …

1 The research on which this report is based was made possible in part through the assistance
of a grant from the National Endowment for the Humanities. The findings and conclusions …

… All research support was provided by Eli Lilly and Company, and Rebecca Robinson is an
employee of Eli Lilly and Company. No authors received financial support for this research …