Background Symptomatic relief is the primary goal of percutaneous coronary intervention (PCI)
in stable angina and is commonly observed clinically. However, there is no evidence …

Background Coronary revascularization guided by fractional flow reserve (FFR) is
associated with better patient outcomes after the procedure than revascularization guided by …

Objectives : The purpose of this study was to develop an adenosine-independent, pressure-derived
index of coronary stenosis severity. Background : Assessment of stenosis severity …

BACKGROUND: Sympathetic overactivation, is reduced by renal denervation in drug-resistant
hypertension. A similar role for renal denervation in heart failure remains unstudied, partly …

Objectives : This study sought to examine the diagnostic accuracy of the instantaneous wave-free
ratio (iFR) and resting distal coronary artery pressure/aortic pressure (P d /P a ) with …

Background Percutaneous coronary intervention (PCI) is frequently performed to reduce the
symptoms of stable angina. Whether PCI relieves angina more than a placebo procedure in …

Objectives : This study sought to determine if adenosine administration is required for the
pressure-only assessment of coronary stenoses. Background : The instantaneous wave-free …

Aims This meta-analysis aims to quantify the association of reduced coronary flow with all-cause
mortality and major adverse cardiovascular events (MACE) across a broad range of …

Background— Lack of re-endothelialization and neointimal coverage on stent struts has
been put forward as the main underlying mechanism leading to late stent thrombosis. …

Importance Computed tomography–derived fractional flow reserve (FFR-CT) is a novel,
noninvasive test for myocardial ischemia. Clinicians using FFR-CT must be able to interpret …