We studied 211 hyperandrogenic women with respect to clinical presentation, basal androgen
levels, and the degree of cortisol and androgen suppression during a 48-h low-dose (2 …

The pancreatic beta cell normally maintains a stable balance among insulin secretion, insulin
production, and insulin degradation to keep optimal intracellular stores of the hormone. …

Objective Phaeochromocytomas and paragangliomas are familial in up to 25% of cases and
can result from succinate dehydrogenase (SDH) gene mutations. The aim of this study was …

Objective Suboptimal management of Parkinson's disease (PD) medication in hospital may
lead to avoidable complications. We introduced an in-patient PD unit for those admitted …

In the short term (< 2 h), proinsulin biosynthesis is predominately glucose regulated at the
translational level; however, the details at the molecular level behind this mechanism are not …

… Through first-hand archaeological research at recipient villages, archaeologists Robert
Skelly and Bruno David investigate the origins of this indigenous maritime trade system, from …

The Lapita expansion took Austronesian seafaring peoples with distinctive pottery eastward
from the Bismarck Archipelago to western Polynesia during the late second millennium BC, …

There is increasing evidence that the effective care of patients with Parkinson's disease
should involve a multidisciplinary team of health professionals, including the neurologist or …

The regulation of proinsulin biosynthesis in pancreatic β-cells is vital for maintaining optimal
insulin stores for glucose-induced insulin release. The majority of nutrient fuels that induce …

This paper reports on the ceramics from Squares A and B of Bogi 1, a newly excavated site
at Caution Bay, south coast of mainland Papua New Guinea. A dense cultural horizon dated …