Antigens recognized by T cells are expressed as peptides bound to major histocompatibility
complex (MHC) molecules. Microcapillary high-performance liquid chromatography-…

Of several thousand peptides presented by the major histocompatibility molecule HLA-A2.1,
at least nine are recognized by melanoma-specific cytotoxic T lymphocytes (CTLs). Tandem …

Background The appropriate treatment for patients in whom reperfusion fails to occur after
thrombolytic therapy for acute myocardial infarction remains unclear. There are few data …

Peptides extracted from HLA-A2.1 class I major histocompatibility complex (MHC) molecules
expressed on the antigen processing mutant CEMx721.174.T2 were characterized by …

Background— The optimal strategy for treating coronary bifurcation lesions remains a
subject of debate. With bare-metal stents, single-stent approaches appear to be superior to …

Background and Purpose—Blood supply through collateral pathways improves regional
cerebral blood flow and may protect against ischemic events. The effect of collaterals on the risk …

Dendritic cells (DC) play an essential role in the initiation of primary T cell responses to
foreign Ag. It is likely that these potent APC are critical in the initiation of immune responses to …

A patient with severe angina will often be eligible for either angioplasty (PTCA) or bypass
surgery (CABG). Results from eight published randomised trials have been combined in a …

Objectives : This study was designed to compare the long-term consequences of percutaneous
transluminal coronary angioplasty (PTCA) and continued medical treatment. Background …

Inherited retinal disease is a common cause of visual impairment and represents a highly
heterogeneous group of conditions. Here, we present findings from a cohort of 722 individuals …