User profiles for Robert C Rintoul

Robert Campbell Rintoul

Professor of Thoracic Oncology, University of Cambridge; Royal Papworth Hospital
Verified email at nhs.net
Cited by 19840

Spatial and temporal diversity in genomic instability processes defines lung cancer evolution

…, J Marshall, T Voet, P Van Loo, DM Rassl, RC Rintoul… - Science, 2014 - science.org
Spatial and temporal dissection of the genomic changes occurring during the evolution of
human non–small cell lung cancer (NSCLC) may help elucidate the basis for its dismal …

Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

T Sethi, RC Rintoul, SM Moore, AC MacKinnon… - Nature medicine, 1999 - nature.com
Resistance to chemotherapy is a principal problem in the treatment of small cell lung cancer
(SCLC). We show here that SCLC is surrounded by an extensive stroma of extracellular …

Mediastinoscopy vs endosonography for mediastinal nodal staging of lung cancer: a randomized trial

JT Annema, JP Van Meerbeeck, RC Rintoul, C Dooms… - Jama, 2010 - jamanetwork.com
Context Mediastinal nodal staging is recommended for patients with resectable non–small
cell lung cancer (NSCLC). Surgical staging has limitations, which results in the performance …

Integrative molecular characterization of malignant pleural mesothelioma

…, AN Husain, HC Silveira, VW Rusch, RC Rintoul… - Cancer discovery, 2018 - AACR
Through a comprehensive integrated genomic study of 74 MPMs, we provide a deeper
understanding of histology-independent determinants of aggressive behavior, define a novel …

[PDF][PDF] Endobronchial ultrasound with transbronchial needle aspiration for restaging the mediastinum in lung cancer

…, A Ernst, M Krasnik, RC Rintoul - Journal of clinical …, 2008 - researchgate.net
Purpose To investigate the sensitivity and accuracy of endobronchial ultrasound–guided
transbronchial needle aspiration (EBUS-TBNA) for restaging the mediastinum after induction …

[HTML][HTML] The UK Lung Cancer Screening Trial: a pilot randomised controlled trial of low-dose computed tomography screening for the early detection of lung cancer.

…, RD Page, MKB Parmar, RC Rintoul… - Health technology …, 2016 - ncbi.nlm.nih.gov
BACKGROUND Lung cancer kills more people than any other cancer in the UK (5-year
survival< 13%). Early diagnosis can save lives. The USA-based National Lung Cancer …

Suitability of endobronchial ultrasound-guided transbronchial needle aspiration specimens for subtyping and genotyping of non–small cell lung cancer: a multicenter …

…, DM Rassl, M Falzon, G Kocjan, RC Rintoul… - American journal of …, 2012 - atsjournals.org
Rationale: The current management of advanced non–small cell lung cancer (NSCLC)
requires differentiation between squamous and nonsquamous subtypes as well as epidermal …

The challenge of NSCLC diagnosis and predictive analysis on small samples. Practical approach of a working group

…, FJF Herth, S Lantuejoul, M Papotti, RC Rintoul… - Lung cancer, 2012 - Elsevier
Until recently, the division of pulmonary carcinomas into small cell lung cancer (SCLC) and
non-small cell lung cancer (NSCLC) was adequate for therapy selection. Due to the …

Efficacy and cost of video-assisted thoracoscopic partial pleurectomy versus talc pleurodesis in patients with malignant pleural mesothelioma (MesoVATS): an open …

RC Rintoul, AJ Ritchie, JG Edwards, DA Waller… - The Lancet, 2014 - thelancet.com
Background Malignant pleural mesothelioma incidence continues to rise, with few available
evidence-based therapeutic options. Results of previous non-randomised studies …

Utility of endobronchial ultrasound-guided transbronchial needle aspiration in patients with tuberculous intrathoracic lymphadenopathy: a multicentre study

…, B Ng, M Wickremasinghe, A Lalvani, RC Rintoul… - Thorax, 2011 - thorax.bmj.com
Background Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA)
has emerged as an important tool for the diagnosis and staging of lung cancer but its role …