Background We hypothesized that mass distribution of a broad-spectrum antibiotic agent to
preschool children would reduce mortality in areas of sub-Saharan Africa that are currently …

We previously reported that laboratory reference strains of Chlamydia trachomatis differing in
infection organotropism correlated with inactivating mutations in the pathogen’s tryptophan …

Background Eye-seeking flies have received much attention as possible trachoma vectors,
but this remains unproved. We aimed to assess the role of eye-seeking flies as vectors of …

Background Trachoma is the leading cause of preventable blindness. Pogrammes to prevent
blindness due to trachoma are based on community-wide treatment with topical tetracycline…

Background Trachoma, caused by repeated ocular infection with Chlamydia trachomatis, is
an important cause of blindness. Current recommended dosing intervals for mass …

Background Domestic flies are accepted vectors of diarrhoea, but their role in trachoma
transmission has never been quantified and no study has shown that fly control decreases the …

Background Antibiotics are an important part of WHO's strategy to eliminate trachoma as a
blinding disease by 2020. At present, who needs to be treated is unclear. We aimed to …

Trachoma is the commonest infectious cause of blindness. Recurrent episodes of infection
with serovars A–C of Chlamydia trachomatis cause conjunctival inflammation in children who …

Background Trachoma, caused by Chlamydia trachomatis, remains the worlds leading infectious
cause of blindness. Repeated ocular infection during childhood leads to scarring of the …

Community control of trachoma as a blinding disease is based on the SAFE strategy of
Surgery, Antibiotic therapy, Facial cleanliness and Environmental improvement. Surgery and …