[HTML][HTML] Treatment of oxaliplatin-induced peripheral neuropathy by intravenous mangafodipir

R Coriat, J Alexandre, C Nicco… - The Journal of …, 2014 - Am Soc Clin Investig
Background. The majority of patients receiving the platinum-based chemotherapy drug
oxaliplatin develop peripheral neurotoxicity. Because this neurotoxicity involves ROS production, …

[HTML][HTML] Sarcopenia predicts early dose-limiting toxicities and pharmacokinetics of sorafenib in patients with hepatocellular carcinoma

O Mir, R Coriat, B Blanchet, JP Durand… - PloS one, 2012 - journals.plos.org
Background Sorafenib induces frequent dose limiting toxicities (DLT) in patients with
advanced hepatocellular carcinoma (HCC). Sarcopenia has been associated with poor …

Actualisation des recommandations de bonne pratique clinique pour l'utilisation de la TEP en cancérologie

…, S Querellou-Lefranc, G Quere, M Wartski, R Coriat… - Bulletin Du Cancer, 2019 - Elsevier
La tomographie par émission de positons (TEP) est une technique d’imagerie fonctionnelle
de médecine nucléaire ayant fait la preuve de son intérêt clinique principalement en …

Sorafenib-Induced Hepatocellular Carcinoma Cell Death Depends on Reactive Oxygen Species Production In Vitro and In Vivo

R Coriat, C Nicco, C Chéreau, O Mir, J Alexandre… - Molecular cancer …, 2012 - AACR
Sorafenib is presently the only effective therapy in advanced hepatocellular carcinoma (HCC).
Because most anticancer drugs act, at least in part, through the generation of reactive …

[HTML][HTML] Deep learning and radiomics predict complete response after neo-adjuvant chemoradiation for locally advanced rectal cancer

…, M Housset, C Durdux, J Taieb, A Berger, R Coriat… - Scientific reports, 2018 - nature.com
Abstract Treatment of locally advanced rectal cancer involves chemoradiation, followed by
total mesorectum excision. Complete response after chemoradiation is an accurate surrogate …

[HTML][HTML] Nab-paclitaxel plus gemcitabine for metastatic pancreatic adenocarcinoma after Folfirinox failure: an AGEO prospective multicentre cohort

…, P Hammel, T Lecomte, J Dréanic, R Coriat… - British journal of …, 2015 - nature.com
Background: There is currently no standard second-line treatment for metastatic pancreatic
adenocarcinoma (MPA), and progression-free survival is consistently< 4 months in this setting…

Efficacy of adjuvant chemotherapy in colon cancer with microsatellite instability: a large multicenter AGEO study

…, I Trouilloud, T Lecomte, R Coriat… - Journal of the …, 2016 - academic.oup.com
Background: Deficient mismatch repair (dMMR) colon cancer (CC) is reportedly resistant to
5-fluorouracil (5FU) adjuvant chemotherapy while preliminary data suggest chemosensitivity …

Gastroenteropancreatic well-differentiated grade 3 neuroendocrine tumors: review and position statement

R Coriat, T Walter, B Terris, A Couvelard… - The …, 2016 - academic.oup.com
In 2010, the World Health Organization (WHO) classification of neuroendocrine neoplasms
was reviewed and validated the crucial role of the proliferative rate. According to the WHO …

Modified FOLFIRINOX versus CISGEM chemotherapy for patients with advanced biliary tract cancer (PRODIGE 38 AMEBICA): a randomized phase II study

…, Y Molin, T Lecomte, F Ghiringhelli, R Coriat… - Journal of Clinical …, 2022 - ascopubs.org
PURPOSE Whether triplet chemotherapy is superior to doublet chemotherapy in advanced
biliary tract cancer (BTC) is unknown. METHODS In this open-label, randomized phase II-III …

Synthesis and selective anticancer activity of organochalcogen based redox catalysts

…, C Scherer, M Abbas, AAP Zada, R Coriat… - Journal of medicinal …, 2010 - ACS Publications
Many tumor cells exhibit a disturbed intracellular redox state resulting in higher levels of
reactive oxygen species (ROS). As these contribute to tumor initiation and sustenance, catalytic …