Interaction of cellular prion and stress-inducible protein 1 promotes neuritogenesis and neuroprotection by distinct signaling pathways

…, AG Muras, GL Mancini, RMPS Castro… - Journal of …, 2005 - Soc Neuroscience
Understanding the physiological function of the cellular prion (PrP c ) depends on the
investigation of PrP c -interacting proteins. Stress-inducible protein 1 (STI1) is a specific PrP c …

Effect of direct transportation to thrombectomy-capable center vs local stroke center on neurological outcomes in patients with suspected large-vessel occlusion stroke …

…, P Castillo, G Castrillo, RM Castro, ME Castro… - Jama, 2022 - jamanetwork.com
Importance In nonurban areas with limited access to thrombectomy-capable centers, optimal
prehospital transport strategies in patients with suspected large-vessel occlusion stroke are …

Towards stronger EU governance of health threats after the COVID-19 pandemic

A Renda, R Castro - European Journal of Risk Regulation, 2020 - cambridge.org
In just a few months, COVID-19–a disease caused by a novel coronavirus known as SARS-CoV-2–appeared
in China and quickly spread to the rest of the world, including Europe and …

[HTML][HTML] Remove obstacles to sharing health data with researchers outside of the European Union

HB Bentzen, R Castro, R Fears, G Griffin… - Nature Medicine, 2021 - nature.com
COVID-19 has shown that international collaborations and global data sharing are essential
for health research, but legal obstacles are preventing data sharing for non–pandemic-…

Mitochondrial replacement therapy: the UK and US regulatory landscapes

RJ Castro - Journal of Law and the Biosciences, 2016 - academic.oup.com
On October 29, 2015, the United Kingdom’s regulations on mitochondrial donation (UK
2015 Regulations) came into force. 1 This amendment to the UK Human Fertilisation and …

The first brown dwarf discovered by the backyard worlds: Planet 9 citizen science project

…, L Trouille, SM Silverberg, R Castro… - The Astrophysical …, 2017 - iopscience.iop.org
The Wide-field Infrared Survey Explorer (WISE) is a powerful tool for finding nearby brown
dwarfs and searching for new planets in the outer solar system, especially with the …

Effects of the COVID-19 pandemic and previous pandemics, epidemics and economic crises on mental health: systematic review

…, P Flodin, A Sidorchuk, L Marchetti, F Awil, R Castro… - BJPsych Open, 2022 - cambridge.org
Background A rise in mental illness is expected to follow the COVID-19 pandemic, which
has also been projected to lead to a deep global economic recession, further adding to risk …

Transferable exclusivity voucher: a flawed incentive to stimulate antibiotic innovation

C Årdal, E Baraldi, R Busse, R Castro, F Ciabuschi… - The Lancet, 2024 - thelancet.com
As antibiotic resistance increases globally, antibiotic innovation is struggling. WHO states
that the antibiotic clinical pipeline is “insufficient to tackle the challenge of increasing …

[HTML][HTML] Dementia pugilistica with clinical features of Alzheimer's disease

…, S Rosemberg, RMRPS Castro… - Arquivos de neuro …, 2007 - SciELO Brasil
A 61-year-old ex-boxer presented with a three-year history of progressive memory decline.
During a seven-year follow-up period, there was a continuous cognitive decline, very similar …

[HTML][HTML] Validation of commonly used reference genes for sleep-related gene expression studies

…, C Guindalini, ML Andersen, RM Castro… - BMC Molecular …, 2009 - Springer
Background Sleep is a restorative process and is essential for maintenance of mental and
physical health. In an attempt to understand the complexity of sleep, multidisciplinary …