The dramatic title—Rhabdomyolysis: the hidden killer—given to a recent review of this condition
emphasised that dissolution of striated muscle fibres, with leakage of muscle enzymes, …

Background Free radical accumulation and oxidative stress have been proposed as contributing
to the progression of amyotrophic lateral sclerosis (or motor neuron disease). A range …

The skeletal muscle ryanodine receptor plays a crucial role in excitation–contraction (EC)
coupling and is implicated in various congenital myopathies. The periodic paralyses are a …

Free radical accumulation and oxidative stress have been proposed as contributing to the
progression of amyotrophic lateral sclerosis (motor neuron disease). A range of antioxidant …

Limb girdle muscular dystrophy type 2L or anoctaminopathy is a condition mainly characterized
by adult onset proximal lower limb muscular weakness and raised CK values, due to …

Background The immune response to an isoform of glutamic acid decarboxylase (GAD),
GAD65, is associated with two clinically distinct diseases, stiff-man syndrome (SMS) and type 1 (…

It has been shown previously that some patients with chronic fatigue syndrome show an
abnormal increase in plasma lactate following a short period of moderate exercise, in the sub-…

OBJECTIVES To examine the proportions of type 1 and type 2 muscle fibres and the degree
of muscle fibre atrophy and hypertrophy in patients with chronic fatigue syndrome in relation …

Serum acetylcholine receptor antibodies were measured serially in myasthenia gravis patients
before and after early extended thymectomy; they received no medication postoperatively…

Background Myotonic dystrophy is the most common inherited form of muscular dystrophy
affecting adults. Its symptoms are not confined to muscle, and variability in their nature and in …