Respiratory mucosal immunity induced by vaccination is vital for protection from coronavirus
infection in animal models. In humans, the capacity of peripheral vaccination to generate …

Wnts control a wide range of essential developmental processes, including cell fate specification,
axon guidance and anteroposterior neuronal polarization. We identified a conserved …

Dynamic chest radiography (DCR) is a real-time sequential high-resolution digital X-ray
imaging system of the thorax in motion over the respiratory cycle, utilising pulsed image …

Introduction Pneumococcal colonisation is regarded as a pre-requisite for developing
pneumococcal disease. In children previous studies have reported pneumococcal colonisation to …

Rationale: Streptococcus pneumoniae serotype 3 (SPN3) is a cause of invasive pneumococcal
disease and associated with low carriage rates. Following the introduction of pediatric 13-…

BACKGROUND: An enterovaginal or vesicovaginal fistula is a complication resulting in
vaginal discharge of succus, urine, or stool that can lead to significant complications. For low-…

Introduction Despite widely available vaccinations, Streptococcus pneumoniae (SPN)
remains a major cause of morbidity and mortality worldwide, causing community-acquired …

Introduction Experimental Human Pneumococcal Challenge (EHPC) involves the controlled
exposure of adults to a specific antibiotic-sensitive Streptococcus pneumoniae serotype, to …

The COVID-19 pandemic has led to a dramatic increase in patients presenting with type 1
respiratory failure. In order to protect our limited critical care capacity, we rapidly developed a …

Objectives/Hypothesis Observed complications during rigid bronchoscopy, including
hypercarbia and hypoxemia, prompted us to assess how well rigid bronchoscopes serve as an …