Background— Essential hypertension (EHT) is a major cardiovascular risk factor, and the
additional presence of type 2 diabetes mellitus (DM2) increases this risk. However, although …

A patient with Type 1 (insulin-dependent) diabetes mellitus developed localised amyloidosis
at the sites of his injections of porcine insulin. A major amyloid fibril protein was extracted …

The obese hyperglycaemic ob/ob mouse exhibits hyperphagia and other abnormalities of
hypothalamic function. We measured hypothalamic concentrations of four peptides implicated …

The Indium-labelled somatostatin analogue pentetreotide has been successfully developed
for imaging of somatostatin receptor positive tumours. However there is significant renal …

A marked pressor response to water drinking has been observed in patients with autonomic
failure and in the elderly, and has been attributed to sympathetic vasoconstrictor activation, …

Observations have been made on a selected series of insulin-dependent patients with
neuropathy, subdivided into three groups: (1) severe autonomic neuropathy with an …

OBJECTIVE Continuous glucose monitoring (CGM) provides far greater detail about fetal
exposure to maternal glucose across the 24-h day. Our aim was to examine the role of …

Objective Patients with acromegaly demonstrate impaired quality of life (QoL), but data on
long‐term QoL changes in treated acromegaly are limited. This study evaluates and identifies …

Amiodarone is used increasingly in a number of cardiac conditions. Amiodarone is heavily
iodinated and can cause thyroid dysfunction. The diagnosis of amiodarone-induced …

During Wallerian degeneration, the Schwann cell basal laminal ensheathment around
myelinated nerve fibres remains after the removal of myelin and axonal debris, forming a …