The risks of poor transition include delayed and inappropriate transfer that can result in
disengagement with healthcare. Structured transition care can improve control of chronic …

Worldwide prevalence of Helicobacter pylori (H. pylori) infection is approximately 50%, with
the highest being in developing countries. We compared cure rates and tolerability (SE) of …

Background Magnetic resonance enterography (MRE) and ultrasound are used to image
Crohn's disease, but their comparative accuracy for assessing disease extent and activity is not …

Objective Crohn's disease (CD) is associated with intestinal dysbiosis, altered blood T cell
populations, elevated faecal calprotectin (FC) and increased intestinal permeability (IP). CD-…

The era of biologic agents for the treatment of Crohn’s disease has brought about significant
benefits for patients, and since the introduction of infliximab at the turn of the century, the …

Objectives To develop an MRI enterography global score (MEGS) of Crohn’s disease (CD)
activity compared with a reference standard of faecal calprotectin (fC), C-reactive protein (…

Glucose-6-phosphatase, an enzyme localized in the endoplasmic reticulum (ER), catalyzes
the hydrolysis of glucose-6-phosphate (G6P) to glucose and inorganic phosphate. In humans…

Objective To determine the existence of mucosal dysbiosis in siblings of patients with
Crohn's disease (CD) using 454 pyrosequencing and to comprehensively characterise and …

Introduction Crohn’s disease (CD) and ulcerative colitis (UC) are chronic, inflammatory bowel
diseases (IBD). Each class and type of medication available for the treatment of IBD has …

Background Crohn’s disease (CD) is a lifelong, relapsing and remitting inflammatory condition
of the intestine. Medical imaging is crucial for diagnosis, phenotyping, activity assessment …