Objective— Long noncoding RNAs (lncRNAs) represent a rapidly growing class of RNA
genes with functions related primarily to transcriptional and post-transcriptional control of gene …

Full genome annotation requires gene expression analysis and elucidation of promoter activity.
Here, we analyzed the expression and promoter of a highly restricted integrin gene, Itga8…

Objective— Smooth muscle calponin (CNN1) contains multiple conserved intronic CArG
elements that bind serum response factor and display enhancer activity in vitro. The objectives …

Objective— Several studies have shown through chemical inhibitors that p38 mitogen-activated
protein kinase (MAPK) promotes vascular smooth muscle cell (VSMC) differentiation. …

Methods We retrospectively analysed data for 2445 consecutive ICU admissions (November
2014 to June 2017). Patients were routinely assessed for delirium, using twice daily …

The primary aim of our study was to establish what proportion of patients in the Emergency
Department (ED) fulfill the criteria for sepsis. All adult patients presenting to ED in two 1-week …

The purpose of this research was to determine the mechanical and transport properties
contributing to fabric comfort for a series of nonwoven fabrics known to resist spray penetration …

The 4C Deterioration model is a point-of-admission tool for predicting in-hospital clinical
deterioration in patients with COVID-19. 1 It was developed and validated using data from the …

There is growing evidence that outcomes in sepsis are improved by early recognition and
treatment. In this study, we assessed junior doctors’ ability to recognise and manage sepsis. …

… Sarah L Cowan Sarah L Cowan Cambridge University Hospitals NHS Foundation Trust, …
maximising the log-rank test for the difference of survival curves in our cohort was 801 nmol/L. …